M.M. Basso.Treatment of Estrogen Receptor-Positive Breast Cancer[J]. Current Medicinal Chemistry . 2013 (5)Lumachi F, Brunello A, Maruzzo M, Basso U, Basso SM. Treatment of estrogen receptor-positive breast cancer. Curr Med Chem 2013; 20: 596-604 [PMID: 23278394 DOI: 10.2174/0929867 ...
The presence of specific estrogen receptors in some tumors indicating hormonal dependency has been shown to be of predictive value for endocrine treatment. This would greatly improve therapeutic planning for patients with breast cancer. Tumor tissue from 52 patients was investigated for content of both...
Brain gray matter alterations have been reported in cross-sectional magnetic resonance imaging (MRI) studies of breast cancer patients after cancer treatme... BC Mcdonald,SK Conroy,TA Ahles,... - 《Breast Cancer Research & Treatment》 被引量: 340发表: 2010年 Distress, psychiatric syndromes, ...
33,34, published preclinical and clinical research suggest a potentially greater benefit for dual- versus single-receptor targeting of HR+/HER2+ breast cancer7,23,35,36. Benefits of such combinations have also suggested potential efficacy in treatment regimens without...
The nonsteroidal antiestrogen tamoxifen has emerged as a highly effective, nontoxic endocrine therapy for women with Stage IV and II estrogen receptor-positive breast cancer. Tamoxifen appears to act by blocking endogenous estrogen action at the target t
Thus, Tamoxifen is a highly effective antitumor agent and is probably the initial treatment of choice for women with hormone responsive breast cancer. Antiestrogen induced objective remissions in 5 of 19 patients who had previously responded to surgical hypophysectomy, and 5 additional patients showed ...
Breast ... S Saez,F Cheix,B Asselain - 《Breast Cancer Research & Treatment》 被引量: 198发表: 1983年 Randomized Trial of Adjuvant Tamoxifen in Node Negative Postmenopausal Breast Cancer The treatment benefit was restricted to patients with ER-positive tumours. There was no significant reduction...
Increased breast cancer risks have been reported among women with gross cystic breast disease (GCBD), although the mechanism for this increase remains unex
Cancer 56(7): 1696-1700, 1985 Google Scholar Goldhirsch A, Gelber RD, Castiglione M: Relapse of breast cancer after adjuvant treatment in premenopausal and perimenopausal women: patterns and prognoses. J Clin Oncol 6: 89-97, 1988 Google Scholar Stewart JF, King RJ, Sexton SA, Millis RR...
Calcitriol (1,25-dihydroxyvitamin D3), the hormonally active form of vitamin D, inhibits the growth of many malignant cells including breast cancer (BCa) c... AV Krishnan,S Swami,D Feldman - 《Steroids》 被引量: 99发表: 2012年 Current medical treatment of estrogen receptor-positive breast ...