This may be explained by the widely existence of ERs in vascular cells both in female and male. Further, our results also showed increased MDA level and decreased SOD activity under IH treatment. Besides, estradiol deficiency increased MDA level, which was rescued by estradiol in vitro. MDA is...
Our results showed that chronic high dose of ES decreased the learning ability of male castrated rats in a reference memory version of MWM test. This can be explained by the decreased AChE activity in the hippocampus.Mohammadi-FaraniPharmaceutical...
Q2, and their interactions as explanatory variables, 47% of the variance of HDLC ( P = 0.006), 76% of the variance of LDLC ( P = 0.0001), 87% of the variance of the ratio of LDLC to HDLC ( P = 0.0001), and 56%of the variance T G ( P = 0.01) could be explained (18). ...
41 However, a systematic review of studies in transdermal HC users compared with users of second-generation oral CHCs concluded that there was good to fair evidence (level II-2) demonstrating conflicting results as to whether women using the patch or the ring have a higher ...
This variation from our results can be explained by the different BMI cut-off values used in classifying the patients involved in addition to different protocols used among the different studies. In our study, no correlation was found between the P/E2 ratio on the day of HCG triggering and th...
The number of factors initiating and stimulating the progression of breast cancer are constantly increasing. Estrogens are a risk factor for breast adenocarcinoma, the toxicity of which increases as a result of metabolism and interaction with other facto
Measurements of insulin levels were also performed during this test, as well as the AUC calculation. Our results show that there were no statistical differences in baseline glucose levels between the groups (Figure 3A). The GTT test revealed differences between the groups (Figure 3B,C; OVX vs....
There is no evidence that the use of natural estrogens results in a different endometrial risk profile than synthetic estrogens of equivalent estrogen dose. Adding a progestogen to estrogen therapy in postmenopausal women has been shown to reduce the risk of endometrial hyperplasia, which may be a ...
Taking into account that E2 levels, which are responsible for increasing PR levels, were suppressed by the treatment, our results could be explained, in part, by the down-regulation of uterine PRB expression. In this context, the regulation of PRB appears to be more sensitive than PRA, ...
This could be explained by the fact that calcium is likely to be the major limiting factor in the activation of PLA2. In summary, we suggest that higher concentrations of PKC and PLA2 were present in the explants treated with E2, and that these enzymes promoted an increase in the ...