All women were postmenopausal, had a serum estradiol level of less than 20 pg/mL, and a minimum of five moderate to severe hot flushes per week or a minimum of 15 hot flushes per week of any severity at baseline. Included in this table are an additional 25 postmenopausal hysterectomized...
ultrasensitive recombinant cell bioassay to study estradiol levels in 20 girls with premature thelarche and 15 normal prepubertal girls less than 3 years of ... KO Klein,JM Brown,KA Soisson - 《Journal of Pediatrics》 被引量: 201发表: 1999年 Effect of Obesity on Estradiol Level, and Its Rela...
incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.Precision:Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level were tested 20 times on...
Postmenopausal estradiol levels are less than 10 pg/ml, follicle-stimulating hormone and luteinizing hormone greater than 20mIU/ml.Results:The estradiol level was greater than 9pg/ml at least once in 42 out of 56 patients. For 75 determinations, the estradiol level ranged from less than 10 to...
The method parameters for data processing were set as follows: retention time range 0.1–20.5 min, mass range 100–1500 Da, retention time tolerance 0.2 min, mass tolerance 0.05 Da, noise elimination level 6, peak intensity threshold 50. The peak width at 5% height and the peak-to-peak ...
Although circulating estrogens exist in a dynamic equilibrium of metabolic interconversions, estradiol is the principal intracellular human estrogen and is substantially more potent than its metabolites, estrone and estriol at the receptor level. The primary source of estrogen in normally cycling adult ...
Although circulating estrogens exist in a dynamic equilibrium of metabolic interconversions, estradiol is the principal intracellular human estrogen and is substantially more potent than its metabolites, estrone and estriol, at the receptor level. The primary source of estrogen in normally cycling adult...
Estrogen administration may lead to severehypercalcemiain patients with breast cancer and bone metastases. If hypercalcemia occurs, use of the drug should be stopped and appropriate measures taken to reduce the serum calcium level. Visual Abnormalities ...
Estradiol benzoate (1S,3aS,3bR,9bS,11aS)-1-hydroxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-yl benzoate Intramuscular injection and subcutaneous injection Irregular menstruation, low-estrogen level Breast swelling, decrease appetite, nausea, stomach upse...
This level of conditioning was therefore used with amphetamine (experiments 5 and 6). Conversely, strong conditioning prevents LI in non-treated controls and thus allows the demonstration of treatment- induced abnormally persistent LI. This level of conditioning was used with MK-801 (experiments 7,...