1 IQVIA, MAT Sales January 2021 About Estelle® / Nextstellis® Developed by Mithra, Estelle® / Nextstellis® is a novel patent protected combined oral contraceptive pill containing 3 mg drospirenone (DRSP) and 15 mg estetrol (E4). E4 is a naturally produced estrogen during pregnancy, ...
Participants used daily diaries to record pill use and vaginal bleeding. We evaluated efficacy outcomes in women 16-35 years and bleeding patterns and safety (adverse events [AEs]) in all participants. We assessed overall and method-failure pregnancy rates using the Pearl Index (PI) and life-...