Also found in: Thesaurus, Medical, Acronyms, Encyclopedia, Wikipedia. Related to ester: Malonic ester, ester hydrolysises·ter (ĕs′tər) n. Any of a class of compounds derived from an oxyacid, usually resulting from the reaction of an oxyacid and an alcohol with the elimination of ...
1961 . General base catalysis of ester hydrolysis . J Am Chem Soc 83 : 1743 – 1750 .Stefanidis, D., and Jencks, W. P. (1993) General Base Catalysis of Ester Hydrolysis, Journal of the American Chemical Society 115, 6045-6050.
For example, a Cu(II) complex accelerates the rate of hydrolysis of several nitrophenyl esters by a factor of 104−105, with at least 50 turnovers and no sign of product inhibition. In the best case, with an added nucleophile that also binds to the metal ion, a rate acceleration of ...
Since ortho ester linkages are affected by acids but are stable in base, by adding a basic compound such as Mg(OH)2 hydrolysis can be controlled even if the matrix is in an aqueous environment; Mg(OH)2 stabilizes the bulk of the matrix and erosion occurs only on the surface where the ...
Neighboring group effects on ester hydrolysis. I. Neighboring hydroxyl groups [5] Glucosides having the hydroxyl groups at C-2 and C-3 individually substituted were treated with N,N-diethylzziriciinium chloride in the presence of concent... Y Shalitin,SA Bernhard - 《Journal of the American ...
Other pathways in the reaction between nitrate esters and alkalis are simple hydrolysis and “β-elimination” – the abstraction of a β-hydrogen atom: simple hydrolysis (Eq. (5)): (5) The elimination of a β-hydrogen atom (Eq. (6)): (6) Both pathways lead to the formation of nitrat...
For this reason, hydrolysis occurs and an ester and an amide are formed along with the release of an alcohol. It is generally done under the influence of some catalyst that may be either an acid or a base total depending on the situation. The reaction can be illustrated in the following ...
The catalytic activity of the succinimide resin for hydrolysis of esters was studied. Our results indicated that succinimide resin with 4.08 % nitrogen content,2.51% residual chlorine content and maximal value in weight was reached by reacting 12 h,it was found stronger peak of amide carbonyl ...
Cleavage of the ester allows for controlled drug release by esterases and hydrolases that are present in acidic endosomes and lysosomes, hydrolytic enzymes in the extracellular membrane or plasma, and, to a lesser extent, acid- or base-catalyzed hydrolysis. Jia et al. [39] conjugated three ...
Reaction Pathways and Energy Barriers for Alkaline Hydrolysis of Carboxylic Acid Esters in Water Studied by a Hybrid Supermolecule-Polarizable Continuum Ap... Reaction pathways, solvent effects, and energy barriers have been determined for the base-catalyzed hydrolysis of two representative alkyl esters ...