The anti-SARS-CoV-2 activity determination was supported by ERDF/ESF project ChemBioDrug CZ.02.1.01/0.0/0 .0/16_019/0000729 and the Institute of Organic Chemistry and Biochemistry of the CAS (RVO 61388963). The Scientific Reports | (2023) 13:9161 | https://doi.org/10.1038/s41598-023-...
Under the assumption that the change of Glu-237 to Gln-237 mimics the electrostatic potential of a fully substrate bound state, the observed rigid and narrow conformation of the pore of the binding pocket sup- ports the concept that it functions as a locking mechanism directed through a ...
The popularity of seafoods is high due to their superb dietary properties and healthy composition. However, it is crucial to understand whether they adequately contribute to our essential nutritional needs. Small amounts of essential metals are indispens
Cró thermal water is medium mineral water that is sulfurous water and also rich in silica and certain cations with important functions in the skin (K+, Na+ and Ca2+) (Table 1) [23]. This composition is responsible for promoting cellular renewal, skin hydration, recovery of cutaneous ...
They often apply "chunking" to improve performance. Chunking consists of processing a few more elements than requested, assuming the caller will soon move forward and access the rest of the sequence. Clojure makes large use of sequences and as a consequence there are many functions devoted to ...
W. Antioxidant functions of phytic acid. Free Radic Biol Med 8, 61–69 (1990). 37. Hawkins, P. T. et al. Inhibition of iron-catalysed hydroxyl radical formation by inositol polyphosphates: a possible physiological function for myo-inositol hexakisphosphate. Biochem J 294 (Pt 3), 929–934 ...
These functions are important to supplement the conventional anticancer clinical methods. EO inhalation and oral administration are tested in preclinical and clinical trials [37] to treat anxiolytic states. Additionally, in respiratory diseases, pain management, and stress alleviation, gentle massage, ...
The other was the potential to support B-cell development from hematopoietic progenitor cells (HPCs). In this case, we purified c-Kit+ lineage− Sca-1+ (KLS) HPCs from the bone marrow of IL-7Rα−/− mice and introduced wild-type (WT) and mutant IL-7Rα chains using a ...