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Reactive oxygen species (ROS) are necessary for various cellular processes. However, excess ROS cause damage to many biological molecules and therefore must be tightly regulated in time and space. Hydrogen peroxide (H2O2) is the most commonly used ROS as second messenger in the cell. It is a ...
Due to electron leakage from the mitochondrial electron transport chain during OXPHOS10, however, or directly resulting from the osmotic stress of activa- tion11–15, reactive oxygen species (ROS), such as hydrogen peroxide (H2O2), may be produced in excess causing depolarisation of the ...
converting superoxide radicals to hydrogen peroxide (H2O2), and then to harmless oxygen and water. Diminished antioxidant enzyme activities likely lead to reduced ROS scavenging, increasing tissue susceptibility to oxidative damage.
Reactive oxygen species (ROS) such as superoxide anion radicals, hydrogen peroxide and hydroxyl radicals are generated during mitochondrial oxidative metabolism, cellular response to xenobiotics, cytokines, and bacterial invasion and/or they may arise from interactions with exogenous sources such as xenobiot...
Although total oxygen radical production by Mac-1−/− and Mac-1+/−PMNs adherent to Ab-coated tumor cells was similar, respiratory burst activity of Mac-1−/− PMNs was detectableoutside PMN–tumor cell complexes. Normally, closed compartments are formed between phagocytes and Ab-...
Like a lightning storm, ozone is created when oxygen is exposed to the discharge of a powerful electric current through air. While widely used in Europe for many years to treat municipal drinking water, it has not had a similar acceptance in the US. Ozone can be used throughout water treat...
Fargašová A, Derco J, Ondrejkovičová I, Havránek E (2000) Effect of Fe(III) complexes with heterocyclic N-donor ligand on iron accumulation and oxygen production by the alga Scenedesmus quadricauda. J Trace Microprobe Tech 18:245–249 Google Scholar Chizzola R, Michitsch H, Franz ...
coli resilience in a hydrogen peroxide (H2O2) survival assay (Fig. 5A). Bacteria from an overnight liquid culture were challenged with incremental concentrations of H2O2 for one hour, after which the reaction was quenched by the addition of excess catalase. Dilutions of the reaction mixtures ...
Tumours contain areas of low oxygen (hypoxia) because cancer cells grow and divide so fast that the blood vessels can't keep up with their oxygen requirement. Cells in a hypoxic region are prone to metastasis, but the reasons for this are unknown. Erler