Practical guidance and considerations for transitioning patients from oxcarbazepine or carbamazepine to eslicarbazepine acetate — Expert opinion There is currently a lack of guidance on methodology and special considerations for transitioning patients from oxcarbazepine (OXC) or carbamazepine (CBZ) ... Jukka...
Carbamazepine (CBZ) and oxcarbazepine (OXC) were purchased from Sigma (Poole, UK). Eslicarbazepine [(+)-(S)-10,11-dihydro-10-hydroxy-5H-dibenzo/b,f/azepine-5-carboxamide] was synthesized in the Laboratory of Chemistry, BIAL – Portela & Cª, S.A., with purity >99.5%. N6-cyclopentyl...
CarbamazepineStatus EpilepticusLamotrigineLevetiracetamPartial SeizureEslicarbazepine acetate (Aptiom) is a once-daily, orally administered antiepileptic drug (AED) approved previously in the EU, USA and several other countries for use as adjunctive therapy for the treatment of partial-onset seizures. Based ...
Gil-Nagel et al., “A post-hoc exploratory analysis of the effect of eslicarbazepine acetate as adjunctive treatment in adult patients with partial-onset seizures refractory to carbamazepine”, 66th American Epilepsy Society Annual Meeting, Nov. 30-Dec. 4, 2012, San Diego, CA, 1 page. Carre...