Dofetilide.The article describes the case of an 83-year-old woman who developed QT interval prolongation because of a dofetilide dose calculation error.EBSCO_AspReactions Weekly
Yen WH, Su YD, Chang YC et al (2013) Sinulanorcembranolide A, a novel norcembranoidal diterpene from the octocoral Sinularia gaweli . Tetrahedron Lett 54:2267–2270Wei-Hsuan Yen,Yin-Di Su,Yu-Chia Chang. Sinulanorcembranolide A, a novel norcembranoidal diterpene from the octocoral ...
TOTAL SYNTHESIS OF (±)TANIKOLIDETOTAL SYNTHESIS OF (±)TANIKOLIDEdoi:10.1081/SCC-120005428tanikolidelactonizationsynthesisA total synthesis of (±)tanikolide 1 is described. The six-membered lactone moiety of the title compound was completed through oxidation of α,δ-dihydroxyl compound by PDC.Ru...
Target site insensitivityImmunohistochemistryCardenolide sequestrationArctiidaeAdaptationDanaus plexippusCardenolides are toxic plant compounds which specifically inhibit Na+/K+-ATPase, an animal enzyme which is essential for many physiological processes, such as the generation of action potentials. Several ...
The article presents a case report involving a 33-year-old man who developed a prolonged corrected QT interval after taking an intentional overdose of dofetilide. It is said that the man took 20 capsules of dofetilide, but then his heart started beating rapidly and did not feel better. It...
AliceDepartmentL.DepartmentRobinsonDepartmentEBSCO_AspPharmacotherapyBova Campbell K, Mando JD, Gray AL, Robinson E.Management of dofetilide overdose in a patient with known cocaine abuse. Pharmacotherapy 27: 459-463, No. 3, Mar 2007 - USA
A novel 2-ketobriarane diterpenoid, briarenolide E (1), was isolated from an octocoral Briareum sp. The structure of briarane 1 was elucidated by interpretations of spectral data. Compound 1 displayed modestly inhibitory effects on the generation of superoxide anions and the release of elastase ...
This article presents a case report involving a male patient who developed QT prolongation and torsades de pointes secondary to acute ischemia during treatment with dofetilide for atrial fibrillation. It provides a background on the medical history of the patient. It describes the symptoms presented...
Focuses on atrial fibrillation in the elderly. Requirement of careful nursing assessment for antiarrhythmic agents; Signs and symptoms of the disease; Complications and treatment of the disease. INSET: Calculating QT and QTc Intervals..BensonLinda McAlpineAmerican Journal of Nursing...
A convergent and highly stereocontrolled synthesis of amphidinolide E (1) has been accomplished. The synthesis features a highly diastereoselective (>20:1) BF3·Et2O promoted [3+2] annulation reaction between aldehyde 3 and allylsilane 4 to afford substituted tetrahydrofuran 2.Porino...