We then sought to use the summation of i-modulons to quantitatively account for these strain-specific differences. To this end, we analyzed two expression profiles in the compendium: the reference condition (wild-typeE. coliMG1655) andE. coliBW25113 with thiamine and ferric chloride supplementati...
coli have increased worldwide and so has the emergence of antibiotic resistant strains. In the present study we have assembled, annotated and analysed genome sequences of three strains of the phylogroup D of E. coli. These strains were isolated from the river Yamuna, a prominent anthropogenic ...
coli subtypes, entero- hemorrhagic E. coli O157:H7, which causes severe enteritis, triggers inflammasome activation.12 However, until very recently, no studies had investigated inflammasome involve- ment in UPEC recognition or UTI. In this study, we show that the genome-sequenced UPEC reference ...
coli were enriched by ultracentrifugation. The effect on the growth and viability of human enterocyte-like Caco-2 cells by OMVs was determined by trypan blue exclusion, MTT and BrdU incorporation assays. The ability of OMVs to induce DNA damage was assayed by single-cell gel electrophoresis, and...
coli (73–89) were also sequenced and compared. Whole genome comparison revealed that three (HMLN-1, PC-1 and KIC-2) of the four TEC strains carried a genomic island that encodes a Type 6 Secretion System that may contribute to adhesion of the bacteria to gut epithelial cells. The ...
(2005) Metabolic engineering of Escherichia coli for enhanced production of succinic acid, based on genome comparison and in silico gene ... H Takaku,N Wakisaka,M Takagi - 《Journal of Biotechnology》 被引量: 31发表: 2010年 Metabolic engineering for the enhanced production of succinic acid ...
To clarify the clinical and bacteriological correlates of urinary-tract infection (UTI) due to Escherichia coli O15:K52:H1, during a 1-year surveillance period we prospectively screened all 1, 871 significant E. coli urine isolates at the Hospital de la Santa Creu i Sant Pau, Barcelona, Spai...
In a whole genome-based phylogeny, clinical and fecal isolates ofEscherichia colisequence type 131 (H30R1 andH30Rx subclones) from six households formed household-specific clusters, interspersed among reference ST131 genomes. This supported the fecal-urethral hypothesis and confirmed within-household str...
coli genome with codon replacements and refactorings; Supplementary Data 3 provides the table of target codons; Supplementary Data 4 provides the table of overlaps and refactoring; Supplementary Data 5 provides the table of 10-kb stretches; Supplementary Data 6 provides the GenBank file of the BAC...
Without antibiotic treatment, acute UTIs in humans either self-resolve or develop into long-lasting chronic infections4. Infection of C3H/HeN mice with uropathogenicEscherichia coli(UPEC) recapitulates these two outcomes. Chronic cystitis in these mice is defined as persistent high titre bacteriuria (...