二、入组患者有明确的ESBL-E感染并且对磷霉素敏感(MIC≤32 mg/L),且接受3—7天经验性治疗达到降阶梯标准,至少满足3项标准:生命体征平稳,已退热,UTI相关症状、WBC和CRP、脓尿/菌尿有改善趋势(白细胞酯酶阴性,尿检WBC减少或阴性,亚硝酸盐阴性,中段尿培养细菌<105/mL,导管尿培养细菌<102/mL)。三、研究排除了单...
Conclusions: Ertapenem is highly effective in treatment of moderately severe ESBL producing gram-negative UTI, excepting Pseudomonas. It shows excellent response to E. coli and Klebsiella species. Being single a dose, it has better patient compliance. The treatment is cost effective compared to other...
二、入组患者有明确的ESBL-E感染并且对磷霉素敏感(MIC≤32 mg/L),且接受3—7天经验性治疗达到降阶梯标准,至少满足3项标准:生命体征平稳,已退热,UTI相关症状、WBC和CRP、脓尿/菌尿有改善趋势(白细胞酯酶阴性,尿检WBC减少或阴性,亚硝酸盐阴性,中段尿培养细菌<105/mL,导管尿培养细菌<102/mL)。三、研究排除了单...
二、入组患者有明确的ESBL-E感染并且对磷霉素敏感(MIC≤32 mg/L),且接受3—7天经验性治疗达到降阶梯标准,至少满足3项标准:生命体征平稳,已退热,UTI相关症状、WBC和CRP、脓尿/菌尿有改善趋势(白细胞酯酶阴性,尿检WBC减少或阴性,亚硝酸盐阴性,中段尿培养细菌<105/mL,导管尿培养细菌<102/mL)。三、研究排除了单...
[12]Khorvash F,Mostafavizadeh K,Mobasherizadeh S,et al.Susceptibility pattern of E.coli-associated urinary tract infection (UTI):a comparison of spinal cord injury-related and nosocomial UTI[J].Med SciMonit,2009,15(11):CR579-CR582.©...
coli [3]. Also, the presence of co-resistance, e.g. co-resist- ance to extended-spectrum cephalosporins and fluoro- quinolones, may exacerbate the trend of treatment and limit antibiotic choice [4]. Aside from clinical infections, the incidence of fecal carriage has recently gained importance....
:The aim of this study was to identify microbial risk factors for treatment failure of pivmecillinam in community-acquired urinary tract infections (ca-UTIs) caused by ESBL-producing Escherichia coli. Eighty-nine ESBL-producing E. coli isolated from women suffering from ca-UTIs were included. Th...
Monitoring of ESBL production and antimicrobial susceptibility testing are necessary to avoid treatment failure in patients with urinary tract infection (UTI). Key words: Extended spectrum, beta-lactamases, urinary tract infections,Escherichia coli, Klebsiella pneumoniae. 展开 关键词: Extended spectrum beta...
Molecular characterization of Extended-spectrum β lactamase- producingE. coli Introduction For decades, antibiotics have been used for the treatment of bacterial infections successfully; however, over the past few years, the abuse of antibiotics has led to the emergence of antimicrobial resistance around...
43:1407–1414.OngoingClinicalStudyonAlternativestoCarbapeneminESBL-producingBacterialInfectionsβ-Lactam/β-LactamInhibitorCombinationsfortheTreatmentofBacteremiaDuetoESBL–ProducingEcoli:APostHocAnalysisofProspectiveCohortsESBL-ECisanimportantcauseofinvasiveinfections.Alternativestocarbapenems—consideredthedrugsofchoice—...