Erythropoietin is a hormone whose production is stimulated by all forms of oxygen deficiency. The main production takes place in specialized fibroblasts in the kidney of adults and in liver cells during the fetal and neonatal period. The most important function of the hormone can be derived from ...
-stimulated EPO production. Anemic hypoxia, induced by 2% (v/w body weight) blood withdrawal, increased serum EPO concentration from 38 卤 2 to 352 卤 76 mU/ml, with the increased serum adenosine concentration in the renal vein. KF17837 (0.1 mg/kg, i.v.), but not KW-3902 (0.1 mg...
erythrocytes as does hypoxia, and hypoxia always induces an increase in plasma lactate levels, it can be deduced that erythropoietin (ESF) production is stimulated by an increase in plasma lactate and not directly by a lack of oxygen... G Frangioni,G Borgioli - 《Journal of Experimental Zoolo...
Erythropoietin is a glycoprotein hormone that regulates red blood cell production in a feedback loop manner between kidney and bone marrow based on oxygen tension. It consists of 165 amino acids and has a molecular weight of 30,000–34,000; approximately 30% is accounted for by covalently linke...
Epoetin alfa serves to restore erythropoietin deficiency in pathological and other clinical conditions where normal production of erythropoietin is impaired or compromised. In anemic patients with chronic renal failure (CRF), administration with epoetin alfa stimulated erythropoiesis by increasing the ...
Erythropoietin (Epo) is a glycoprotein that promotes the proliferation and differentiation of erythrocyte precursors. The major site of Epo production is the kidney, while the liver is the main extrarenal site of Epo production. Within these organs, the cells synthesizing Epo were identified by usin...
Answer to: The production of red blood cells is stimulated by ___. (a) low-density lipoproteins (b) immunoglobulins (c) erythropoietin (d)...
Despite the clear link between EPO and RBCs, MDS patients with similar hemoglobin levels can have very different sEPO levels [44,74]. Many, but not all, MDS patients with anemia have elevated sEPO levels, as EPO production is stimulated by hypoxemia [12]. However, despite these high sEPO ...
Added erythropoietin stimulated erythroid precursor DNA synthesis and cell replication. The erythropoietin effect was inhibited by a rabbit antibody to human erythropoietin. The culture system provides a means to study directly normal and abnormal human erythropoiesis in vitro. 展开 ...
Which of the following hormones is not secreted by the placenta during pregnancy? (a) Human placental lactogen (b) Androgens (c) Estradiol (d) Progesterone (e) Inhibin. Estrogen production cannot occur when which of the following hormone(s) is/are ...