Complement is implicated in the pathogenesis of systemic lupus erythematosus (SLE) in several ways and may act as both friend and foe. Homozygous deficiency of any of the proteins of the classical pathway is ca
"Cenerimod acts on both T cells and B cells and at a fundamental stage in the autoimmune response, meaning it has the potential to alter the course of lupus. Cenerimod showed the potential to modify several inflammatory pathways demonstrating its broad immune-modulatory pharmacodynamics. In our Pha...
For severe cases of lupus and sometimes you may hear them referred to as “steroid-sparing” meaning the use of them helps lower the amount of steroids the patient may have to take. Remember steroids can cause adverse side effects. Educate about preventing infection and monitoring self for infe...
However, the average time between diagnosis of SLE and presentation with lupus enteritis is around 44 months, meaning that isolated enteritis as a first presentation of SLE is extremely rare. Only two out of 150 patients reviewed by Janssens et al (from a single tertiary lupus centre) presented...
(26.8) 0.009 Unspecified complications 111 (6.2) 406 (1.7) 0.233 107 (6.0) 99 (5.6) 0.019 Comorbidities Hypertensive diseases 927 (52.1) 9928 (42.0) 0.204 923 (52.0) 963 (54.3) 0.045 Disorders of lipoprotein metabolism and other lipidemia 775 (43.6) 6299 (26.6) 0.360 773 (43.5...
Learn about systemic lupus erythematosus (SLE) causes, signs, symptoms, complications, medications, and treatment information. See pictures of common lupus skin rashes.
You may explain that lupus is somewhat of a misguided immune system that causes one’s own immune system to attack its otherwise healthy body parts. Lupus is chronic, meaning it lasts throughout life. It may help to explain that lupus is unpredictable and takes on many symptoms. ...
Although the term is frequently used alone to designate lupus vulgaris and sometimes lupus erythematosus, without a modifier it has no meaning. The Latin word lupus means wolf; erythematosus refers to redness. The name lupus erythematosus has been used since the 13th century because physicians ...
Although the term is frequently used alone to designate lupus vulgaris and sometimes lupus erythematosus, without a modifier it has no meaning. The Latin word lupus means wolf; erythematosus refers to redness. The name lupus erythematosus has been used since the 13th century because physicians ...
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as is commonly understood by one of ordinary skill in the art. All patents, applications, published applications and other publications are incorporated by reference in their entirety. In the event that ...