Shake well to dissolve and immediately transfer contents of the reconstituted vial to 50 mL of 0.9% Sodium Chloride Injection. Complete the infusion within 6 hours of reconstitution. Preparation for intramuscular administration: ERTAPENEM FOR INJECTION MUST BE RECONSTITUTED PRIOR TO ADMINISTRATION. Recon...
Ertapenem demonstrated the greatest stability in 0.9% and 0.225% sodium chloride solutions. Ertapenem sodium injection 10 and 20 mg/mL are relatively stable in sodium chloride injections and Ringer‘s solution when stored at 25 and 4 °C, but are unstable in mannitol and dextrose solutions. The...
Use caution in renal impairment; adjust dose in moderate to severe renal dysfunction Carbapenem use may decrease serum levels of divalproex sodium or valproic acid Pregnancy and Lactation Available data from a small number of post-marketing cases with use in pregnancy are insufficient to inform any ...
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The reconstituted solution, immediately diluted in 0.9% Sodium Chloride; Injection, may be stored at room temperature (25 deg C) and used within 6 hours or stored for 24 hours under refrigeration (5 deg C) and used within 4 hours after removal from refrigeration. Solutions of ertapenem; shoul...
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This route is to perform a condensation reaction between MAP and side chains in N,N-dimethylformamide (DMF) as a solvent under the action of tetramethylguanidine at low temperature, and drop an appropriate amount of sodium bicarbonate solution to obtain Ertapenem sodium with protective group is the...
Ertapenem disodium (Subcutaneous injection, 4h after infection, systemic infection model) is active against all gram-positive organisms, and is also active against gram-negative organisms tested with ED50s of <0.25 mg/kg/dose. 相关产品:Rapamycin | Chloroquine | Doxorubicin hydrochloride | Bafilomycin...
As no potassium was included in this assay only the sodium ions of hydrolysed ertapenem with the m/z ratios of 450.5, 472.5, 494.5, 516.5 and 538.5 were detected. The hydrolysis was inhibited by APBA (Figure 1, bottom) as only the unhydrolysed forms of ertapenem were detected with the m...
The invention provides an ertapenem sodium freeze-dried preparation and a preparing method thereof. The preparing method comprises the following steps: (1) at the temperature of -3 DEG C to 10 DEG C, adding a carbon dioxide source and ertapenem sodium into water for injection, dissolving, and...