Morré DJ, Morré DM (1993) Cell-free analysis of ER to Golgi apparatus vesicular traffic. In: Morré DJ, Howell K, Bergeron JJM (eds) Molecular mechanisms of membrane traffic. Springer, Berlin Heidelberg New York Tokyo, pp 1–15 (NATO ASI series, series H, vol 74)...
Consistent with this finding, cyclin FS621G also induces fragmentation of the Golgi apparatus and activates ER stress, ER-associated degradation, and apoptosis. Induction of Golgi fragmentation and ER stress were confirmed with a second ALS/FTD variant cyclin FS195R, and in cortical primary neurons...
Similarly, proper functioning of the Golgi apparatus is closely linked to cellular viability22, and its unique morphology, with tethered stacks of cisternae, is required for function. However, the Golgi apparatus can undergo disassembly and fragmentation into condensed, tubulovesicular punctate structures...
At the end of the 19th century, Camillio Golgi impregnated Purkinje cells with silver salts to reveal a network of interconnected structures: the internal reticular apparatus. Adaptation of Golgi’s method for electron microscopy demonstrated that metal staining specifically occurred in the cis-most ci...
Stefano G, Renna L, Moss T, McNew JA, Brandizzi F . In Arabidopsis, the spatial and dynamic organization of the endoplasmic reticulum and Golgi apparatus is influenced by the integrity of the C-terminal domain of RHD3, a non-essential GTPase.Plant J2012;69: 957–966. ...
Palmitoylation of GAP-43 by the ER-Golgi intermediate compartment and Golgi apparatus. Palmitoylation of the neuronal plasticity protein GAP-43 has previously been shown to occur at the plasma membrane, but the site of initial palmitoylation ......
The protein is known to be transported from the ER to the Golgi apparatus via the perinuclear and peripheral ERGIC (n/ph-ERGIC) in a temperature-dependent manner. At 15 °C, transport of VSVG proteins is initiated from the ER to the Golgi, but the protein accumulates in the n/ph-ERGIC...
Introduction Cell division is associated with changes in the morphology and function of intracel- lular membrane structures, including the endocytic system, the Golgi apparatus and the endoplasmic reticulum (ER). In species with an open mitosis, the nuclear envelope (NE) breaks up early in mitosis...
1f). ERES are specialized ER domains that form transport carriers with protein cargoes destined for secretion via the Golgi apparatus53. Our screen identified most ERES proteins as required for GPAT4 targeting to LDs, including Sec12, Sec16, Tango1 and COPII coat components (Sar1, Sec23, Sec...
The finally misfolded/unfolded proteins would be degraded by the ERAD pathway, and the properly folded/assembled cargoes are packaged into the COPII vesicles and sorted to the Golgi apparatus for further sorting to the plasma membrane or vacuole/lysosome pathway6,7,8,9. Two ER exit mechanisms, ...