The endoplasmic reticulum(ER) membrane protein complex(EMC) regulates the synthesis and quality control of membrane proteins with multiple transmembrane domains. One of the membrane spanning subunits, EMC3, is a core member of the EMC complex that provides essential hydrophilic vestibule for substrate ...
英文名称:ER Membrane Protein Complex Subunit 8 (EMC8) Antibody,中文名称:内质网膜蛋白复合物8亚单位(EMC8)抗体,产品货号:Catalogue No: abx242044,EMC8抗体是一种抗EMC8的兔多克隆抗体。目标EMC8人、小鼠、大鼠宿主兔克隆性多克隆试
英文名称:ER Membrane Protein Complex Subunit 1 (KIAA0090) Antibody,中文名称:ER膜蛋白复合物亚单位1(KIAA0090)抗体,产品货号:Catalogue No: abx036785,兔抗KIAA0090蛋白多克隆。目标KIAA0090反应性人宿主兔克隆性多克隆试验应用-酶
The assembly of nascent proteins into multi-subunit complexes is a tightly regulated process that must occur at high fidelity to maintain cellular homeostasis. The ER membrane protein complex (EMC) is an essential insertase that requires seven membrane-spanning and two soluble cytosolic subunits to fu...
protein overload in the ER. Likewise, the PERK–PI3K–AKT1 axis blocks apoptosis, and the PERK–RAF1–RRAS–MAP kinases cascade activates two cardinal transcription factors, ATF4 and NFE2L2, which transactivate genes encoding proteins involved in autophagy. mTOR complex 1 (mTORC1) is a negative...
英文名称: ER membrane protein complex subunit 1 isoform 3 precursor (640-648) 英文同义词: ER membrane protein complex subunit 1 isoform 3 precursor (640-648) CAS号: 分子式: 分子量: 0 EINECS号: Mol文件: Mol File ER membrane protein complex subunit 1 isoform 3 precursor (640-648) 信...
The translocon-associated protein (TRAP) complex resides in the endoplasmic reticulum (ER) membrane and interacts with the Sec translocon and the ribosome to facilitate biogenesis of secretory and membrane proteins. TRAP plays a key role in the secretion of many hormones, including insulin. Here we...
The TAF1 gene encodes TFIID subunit 1 (EC 2.7.11.1, p250, 1872aa), the largest component and core scaffold of the transcription factor complex and has domains with Ser/Thr kinase activity. TAF2 encodes subunit 2 (1199aa), TAF3 encodes sbunit 3 (140 kDa TATA box-binding protein-...
The cytosolic domain of Sec61ß also serves as GDP-exchange factor for the ß subunit of SRP receptor in the ER membrane [16]. In addition to its function in translocation, SBH1 also interacts both genetically and physically with the exocyst, a protein complex required for fusion of ...
Assembly of yeast Sec proteins involved in translocation into the endoplasmic reticulum into a membrane-bound multisubunit complex. Nature 349, 806–808 (1991). Article ADS CAS Google Scholar Panzner, S., Dreier, L., Hartmann, E., Kostka, S. & Rapoport, T. A. Posttranslational protein ...