James E. RobinsonSpringer-VerlagCancer Immunology and ImmunotherapyKirkwood JM, Robinson JE. Human IgG and IgM monoclonal anti- bodies against autologous melanoma produced by Epstein-Barr-virus- transformed B lymphocytes. Cancer Immunol Immunother 1990;32:228-34....
Pharyngitisand abnormal LFTs are tip-offs toward IM rather thanGAS pharyngitis. Roommates, household contacts: no increased risk IM routinely. EBV-specific antibody profile is helpful, especially if heterophile (-) IM. EBV capsid IgM & IgG (+) with EBNA (-) = IM-if sx < 4-6wks. ...
Persons infected with EBV form IgG and IgM antibodies to viral capsid antigens (VCAs) soon after infection [37]. About 80% form antibodies to early antigens (EAs), which usually decrease to undetectable levels 6 months after infection. The presence of antibodies to EAs at later times after ...
EBV capsid IgM and IgG (+) with negative EBNA diagnostic of acute infection if performed < 4-6 wks from the onset of symptoms. This test may be ordered instead of Monospot, often the test of choice in many European countries. Positive EBNA in patients suspected of IM (< 4-6wks sx) ...
Epstein-Barr virus (EBV) has been implicated in multiple sclerosis (MS) pathogenesis. We aimed to assess the frequency of EBV-specific IgG and IgM oligoclonal bands (OCB) in cerebrospinal fluid (CSF) of 50 patients with clinically isolated syndrome (CIS) and in 27 controls with Guillain-Barr...
Sera from 126 patients with nasopharyngeal carcinoma (NPC), 48 other cancers (OC) and 54 normal controls (NC) were collected at the National Taiwan University Hospital and tested for immunoglobulin levels as well as for IgG and IgA antibodies against Epstein-Barr virus (EBV) capsid antigen (VCA...
文章使用间接免疫荧光法对选取的20名多发性硬化症患者和20名其他神经系统疾病患者的脑脊液(CSF)中的抗EBV衣壳抗原(EBV-CA)的免疫球蛋白G(IgG)、抗EBV-CA的IgG亲和力、抗EBV-CA的免疫球蛋白M(IgM)、抗EBV的早期抗原IgG(EBV-EA)和抗EBV核抗原(EBNA)的IgG进行了测试。根据脑脊液中抗体的类型,分析了两...
Epstein-Barr Virus Nuclear Antigen (EBNA) Antibody (IgG) - Primary infection by EBV causes infectious mononucleosis, usually a self-limiting disease in children and young adults. Infection with EBV can cause lymphoproliferative disorders including tumors. EBNA IgG typically appears du...
mainly includes the exploration of three or four markers using automated immunoassays: anti-viral capsid antigen (VCA) or total anti-EBV immunoglobulin M (IgM), anti-VCA, anti-early antigen (EA) or total anti-EBV immunoglobulin G (IgG), and anti-Epstein–Barr nuclear antigen (EBNA)-1 IgG....
EB virus enters the body through the mouth and establishes a productive infection in the pharyngeal epithelial cells. B-cells become infected and are disseminated throughout the body via the bloodstream. During acute primary infection, IgA, IgM and IgG to VCA as well as IgG to EA(D) and MA...