Erythropoietin (EPO) is a 30.4 kDa glycoprotein produced by the kidney, and is mostly well-known for its physiological function in regulating red blood cell production in the bone marrow. Accumulating evidence, however, suggests that EPO has additional organ protective effects, which may be useful...
1/3 REVIEW Open Access Erythropoietin (EPO) in acute kidney injury Elizabeth Moore, Rinaldo Bellomo* Abstract Erythropoietin (EPO) is a 30.4 kDa glycoprotein produced by the kidney, and is mostly well-known for its physiological function in regulating red blood cell production in the bone marrow...
peritubular cells of the kidney,6 although other neurons express high levels of EPO, whereas EPO-r appears organs, notably the liver7 and the spleen, also produce EPO to be strongly expressed on neurons, glial cells, and en- in response to severe reductions in hemoglobin concentra- dothelial...
Human erythropoietin (EPO) is an acidic glycoprotein. It is mainly produced by the kidney. As the primary regulator of the production of red cells,its major functions are to promote erythroid progenitor cells differentiation and to start the synthesis o
Erythropoietin (EPO) is a 30.4 kDa glycoprotein produced by the kidney, and is mostly well-known for its physiological function in regulating red blood cell production in the bone marrow. Accumulating evidence, however, suggests that EPO has additional organ protective effects, which may be useful...
20 H2O2 production in vitro varies with PO2, and H2O2 suppresses EPO expression.21 The clear physiologic importance of O2 and lack of knowledge of SOD3 in the kidney led us to study its role in the mouse. On finding its colocalization with EPO, we postulated a function for SOD3 in the...
Erythropoietin (EPO) is a glycoprotein hormone produced primarily in the adult kidney. It is the principal growth factor regulating the production of circulating erythrocytes. EPO acts remarkably specifically on erythroid progenitor cells, due to their tissue-specific expression of the erythropoietin recept...
Measuring blood levels of erythripoietin, a hormone involved in red blood cell production, can diagnose some medical conditions. Erythropoietin (EPO) is a hormone secreted by specialized cells in the kidney that stimulate the bone marrow to manufacturered blood cells(erythrocytes). ...
Erythropoietin (EPO) in acute kidney injury Erythropoietin (EPO) is a 30.4 kDa glycoprotein produced by the kidney, and is mostly well-known for its physiological function in regulating red blood cel... E Moore,R Bellomo - 《Annals of Intensive Care》 被引量: 199发表: 2011年 Shared and un...
Erythropoietin (EPO) is a growth factor mainly produced in the kidney and with a well-known activity on erythropoiesis. The EPO receptor (EPOR) is differentially expressed in neurons, astrocytes, and endothelial cells in different regions of the central nervous system (CNS) [9]. Different functio...