22. Elliott S, Pham E, Macdougall IC, Elliott S, Pham E, Macdougall IC: Erythropoietins: a common mechanism of action. Exp Hematol 2008, 36:1573-84. 23. Salahudeen AK, Haider N, Jenkins J, Joshi M, Patel H, Huang H, et al: Antiapoptotic properties of erythropoiesis-stimulating ...
Mechanism of Action Peroxidase inhibitors Orphan Drug Status Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases. No New Molecular Entity Yes Highest Development Phases Discontinued Asthma; Ulcerative colitis Most Recent Events 05 Sep ...
The Biogenesis of Erythropoietin.Experimental Hematology 1980; Suppl 8: 1-13. 7. Spivak, J.L. The Mechanism of Action of Erythropoietin. Int J Cell Cloning 1986; 4: 139-166. 8. Erslev, A.J. Erythropoietin. New Eng J Med 1991; 324:1339-1344....
Its mechanism of action is based on the proliferation of erythroid progenitors in the bone marrow, resulting in replication and maturation towards functional erythrocytes. hEpo has widely been used to treat chronic kidney disease, anemia of cancer and anemia associated with chemotherapy. Carbohydrates ...
展开更多 Objective To investigate the mechanism of action of electroacupuncture(EA)at Baihui,Shuigou,Zusanli,and Quchi points in the treatment of cerebral ischemia based on the hypoxia-inducible factor-1α(HIF-1α)-vascular endothelial growth factor(VEGF)-erythropoietin(EPO)signal...MORE 作者 ...
In this review, we will discuss the current efforts and prerequisites of novel growth factor therapies for neurodegenerative diseases with regard to their possible mechanism of action on the molecular level and their effects on brain-derived stem cell populations. Additionally, we will describe the ...
The aim of this study was to investigate the protective effect and mechanism of EPO on the apoptosis induced by high levels of glucose in retinal ganglial cells (RGCs). High glucose-induced apoptosis model was established in RGCs isolated from SD rats (1–3days old) and identified with Thy...
An agent for the treatment of obesity of central action. The mechanism of action is due to the selective inhibition of the reuptake of serotonin and norepinephrine, to a lesser extent – dopamine. Accelerates the onset and prolongs the feeling of fullness, which leads to a decrease in food in...
hypertension, stimulating angiogenesis, and inducing proliferation of smooth muscle fibers. It has also been shown that erythropoietin can increase iron absorption by suppressing the hormone hepcidin. Erythropoietin has been shown to interact with the Erythropoietin receptor as its mechanism of action ...
hypertension, stimulating angiogenesis, and inducing proliferation of smooth muscle fibers. It has also been shown that erythropoietin can increase iron absorption by suppressing the hormone hepcidin. Erythropoietin has been shown to interact with the Erythropoietin receptor as its mechanism of action ...