口服Inspra含有25mg,50mg或100mg依普利酮,建议起始剂量为每天一次50毫克。在4周内,全部治疗效果显而易见。批准日期:2002年09月27日公司:辉瑞公司 INSPRA(依普利酮[eplerenone])片,供口服使用美国初次批准:2002年作用机理依普利农与盐皮质激素受体结合并阻断醛固酮的结合,醛固酮是肾素-血管紧张素-醛固酮系统(RAAS)的...
产地国家:瑞士 处方药:是 所属类别:25毫克/片 30片/盒 包装规格:25毫克/片 30片/盒 计价单位:盒 生产厂家中文参考译名: 辉瑞
The absolute bioavailability of eplerenone is 69 % following administration of a 100 mg oral tablet. Both peak plasma levels (Cmax) and area under the curve (AUC) are dose proportional for doses of 25 mg to 100 mg and less than proportional at doses above 100 mg. Upon repeat dosing, ...
药品名称EPLERENONE 申请号078482产品号001 活性成分EPLERENONE市场状态处方药 剂型或给药途径TABLET;ORAL规格25MG 治疗等效代码AB参比药物否 批准日期2008/07/30申请机构APOTEX INC 化学类型审评分类 与本品相关的专利信息(来自橙皮书Orange Book) 专利号专利过期日是否化合物专利是否产品专利专利用途代码专利下载 ...
包装规格:10-25-50-100mg 品牌:RHINO 质量标准:0.99 瑞诺医药---专注医药杂质对照品、标准品服务方案: 现货供应以下相关杂质: 伊达比星 伊立替康 瑞卢戈利 达格列净 甲泼尼龙 立他司特 骨化二醇 地屈孕酮 度骨化醇 甲氨喋呤 艾拉莫德 尼卡地平 硝苯地平 碘普罗胺 雷替曲塞 托法替尼 胸腺法新 左旋...
Brand name: Inspra Dosage form: oral tablet (25 mg; 50 mg) Drug classes: Aldosterone receptor antagonists, Potassium-sparing diureticsMedically reviewed by Drugs.com on Mar 10, 2025. Written by Cerner Multum.Uses Side effects Warnings Before taking Dosage Interactions What...
Banas J, White H, Parkhomenko A, Patni R, Mukherjee R, Zannad F. Favorable outcomes with 25 mg of eplerenone in patients with post-AMI heart failure: Results from the EPHESUS trial [abstract]. J Cardiac Fail 2005; 11 (Suppl): S156....
Tablet 25 mg 50 mg Adult: Hypertension (HTN) Initial 50 mg orally once daily; may increase to 50 mg orally every 12 hours; may take up to four weeks for a full therapeutic response; hyperkalemia may occur with doses above 100 mg/day ...
For oral administration, the pharmaceutical composition may be in the form of, for example, a tablet, capsule, suspension or liquid. The pharmaceutical composition is preferably made in the form of a dosage unit containing a particular amount of the active ingredient. Examples of such dosage units...
The hepatic first-pass metabolism of EPL is 12.6% and 27.1% under fasted and fed conditions, respectively, with a significant effect on drug bioavailability (69% for a 100 mg oral tablet). EPL is mainly excreted in urine with a t1/2 of 3 to 6 hours [14]. For efficient absorption ...