上皮细胞间质转型(epithelial-mesenchymal transitions, EMT)是一种生物学过程,其中具有极性的上皮细胞转变为具有运动能力的间质细胞,同时获得侵袭和迁移的能力。这一过程对于人体的多个生理和病理状态至关重要。EMT的发生涉及到复杂的信号转导途径和多种分子机制。这些机制与钙连接素、生长因子、转录因子...
总的来说,Epithelial-Mesenchymal Transition 是一个重要的生物学过程,在胚胎发育、伤口愈合和疾病进展中起到关键作用。它涉及复杂的信号通路和转录因子调控网络,对细胞特性的改变具有深远影响。对EMT的深入研究有助于理解相关疾病的发生发展机制,并可能为疾病治疗提供新的策略。
解析 epithelial-to-mesenchymal transition 上皮细胞向间充质细胞转化; 分析总结。 上皮细胞向间充质细胞转化结果一 题目 epithelial-to-mesenchymal transition是什么意思 答案 epithelial-to-mesenchymal transition上皮细胞向间充质细胞转化; 相关推荐 1epithelial-to-mesenchymal transition是什么意思 ...
25, 26 In analogy to tubular EMT, we hypothesized that mesenchymal transition of podocytes after injury may play a vital role in causing podocyte dysfunction that ultimately leads to a defective glomerular filtration. In this study, we have investigated the possibility of podocyte EMT in a ...
Recent studies have indicated that m6A modifications of mRNA are increased in cancer cells during EMT and are functional to EMT induction and cancer progression. Epithelial-mesenchymal transition (EMT) is a cellular process involved in many physiological and pathological conditions. Indeed, MLL3 loss ...
EMT是指上皮细胞在特定信号刺激下,通过一系列分子机制转变为间充质细胞表型和功能的过程。在细胞形态上,上皮细胞转变为更迁移和侵袭性的间充质细胞形态。这种转化过程对于胚胎发育中的组织重塑和器官形成至关重要。二、EMT的分子机制 EMT的发生涉及多个关键分子的调控,包括转录因子、生长因子、细胞外基质...
魏炽炬Epithelial–MesenchymalTransitionOriginofEpitheliumandMesenchyme•Therearetwomajortypesofcellarrangementsintheembryo:•epithelialcell..
Vimentin antibody [GT812] (GTX629744) alpha Smooth Muscle Actin antibody(GTX100034) N-Cadherin antibody(GTX127345) Fibronectin antibody [N1N2], N-term(GTX112794)
结论TP可能通过抑制TGF-β/Smad信号通路缓解高糖诱导的足细胞转分化。 关键词: 雷公藤内酯醇 糖尿病肾病 足细胞 转分化 DOI: 分类号: 基金项目:浙江省中医药科学研究基金计划(A类);杭州市科委医疗卫生及重点专科专病科研攻关专项Effect of triptolide on epithelial to mesenchymal transition (EMT) of mouse ...
“Epithelial-to-mesenchymal transition” (EMT) is a reversible, dynamic cellular program during which either healthy or neoplastic epithelial cells transform into a more motile, invasive, and aggressive mesenchymal cell type. From:Cancer Letters,2019 ...