However, the identity of epithelial progenitor cells that contribute to the proximalization of distal lung tissue and the mechanisms that regulate their fate during tissue remodeling remain poorly defined. Mirroring what occurs in injured or infected human lungs, acute lung injury in mice infected ...
Epithelial tissue functions to absorb, secrete, and excrete substances. In the intestines, this tissue absorbs nutrients duringdigestion. Epithelial tissue in glands secretehormones, enzymes, and other substances. Epithelial tissue in the kidneys excrete wastes, and in the sweat glands excreteperspiration...
Each shown tissue is either in the initial (epiblast (Epi)), intermediate (posterior epiblast (pEpi)) or final state (AME, definitive endoderm, lateral plate mesoderm (LPM) and nascent endothelium (NE)). c, UMAP showing CellRank’s fate probabilities for different tissues as pie charts (n...
Stem Cells and Organoids to Study Epithelial Cell Biology in IBD. In Crohn's Disease and Ulcerative Colitis: From Epidemiology and Immunobiology to a Rational Diagnostic and Therapeutic Approach; Baumgart, D.C., Ed.; Springer: Cham, Switzerland, 2017; pp. 167-172....
they participate in the formation of connective tissue. In addition to these morphological differences, epithelial and mesenchymal cells differ significantly in their functional phenotypes: mesenchymal cells are more motile and invasive than epithelial cells and thus can disperse easily throughout the body...
【医学英文课件】 Histology – Epithelial Tissue Histology–EpithelialTissue Biology2121 •Histology Introduction •Thereare(4)typesoftissue:–1.Epithelial–2.Connective–3.Muscle–4.Nervous •Similaritiesbetweentissuetypes:–1.Allcontaincells–2.Cellsthatmakeuptissues havesimilarfunctions Characteristicsof...
【医学英文课件】 Histology – Epithelial Tissue Histology–EpithelialTissue Biology2121 EpithelialStructure Apical BasementMembrane Apical BasementMembrane •Theepithelialcellslieonthereticularlamina(collagen–CT)•ReticularlaminaisboundtoanotherCTcalledareolarCT.•Togetherthisstructureiscalledthe"basementmembrane”C...
colon and ovarian cancer. Epithelial cell adhesion molecule is a well-known antigen that plays an important role human colon carcinoma tissue [50]. This molecule has gained enormous interest for novel cancer targeting, especially for breast cancer cell surface [51] and efficiently appl...
et al. Induction of expandable tissue-specific stem/progenitor cells through transient expression of YAP/TAZ. Cell Stem Cell 19, 725–737 (2016). Article CAS PubMed PubMed Central Google Scholar Mohyeldin, A., Garzon-Muvdi, T. & Quinones-Hinojosa, A. Oxygen in stem cell biology: a ...
Centre for Craniofacial and Regenerative Biology, King’s College London, London, UK Geraldine M. Jowett, Michael D. A. Norman, Tracy T. L. Yu, Suzette T. Lust, Eva Hamrud, Daniele Marciano, Ricardo M. P. da Silva & Eileen Gentleman ...