The cell of origin of the different histotypes of epithelial ovarian cancer (EOC) has been debated for some time. The dogma for nearly 50 years has been that EOCs develop from the ovarian surface epithelium (OSE), a single layer of mesoepithelial cells with multipotent properties. More ...
Since the last seminar publication 4 years ago,1 there have been major improvements in the understanding of the biology of invasive epithelial ovarian cancer (EOC) (figure 1), and this knowledge has led to changes in clinical practice. This Seminar will summarise the current optimal evidence-base...
Epithelial ovarian cancer (EOC) is a deadly disease with limited diagnostic biomarkers and therapeutic targets. Here we conduct a comprehensive proteomic profiling of ovarian tissue and plasma samples from 813 patients with different histotypes and therapeutic regimens, covering the expression of 10,715 ...
Epithelial ovarian cancer clinical [Abstract] epithelial ovarian cancer is the most common group of ovarian tumors, derived from the ovarian germinal epithelium. There to the characteristics of renal tubular differentiation. Tumor volume is often large, mostly cystic, single room or multiple rooms. The...
Relative to women seronegative to all infections, strongest associations were observed for seropositivity toplus another STI (2.74 [1.20–6.27];alone, 1.88 [1.03–3.42]; all cases); however, the RRs were not significantly different.infection may increase ovarian cancer risk; additional studies are ...
This is the most common type ofovarian cancer. It begins on the outside of theovaries, and it’s named for the cells that make up the surface. Those are called epithelial cells (pronounced eh-pih-THEE-lee-al). As thecancerdevelops, it can spread into other organs. ...
Epithelial ovarian cancer (EOC) is a deadly disease with limited diagnostic biomarkers and therapeutic targets. Here we conduct a comprehensive proteomic profiling of ovarian tissue and plasma samples from 813 patients with different histotypes and thera
There are several different types of ovarian cancers depending upon the cell type of origin. Epithelial cell ovarian cancer (EOC) constitutes 90% of ovarian cancers, while gonadal-stromal (6% occurrence), and germ cell (4% occurrence) tumors make up the rest of the incidence of ovarian cancer...
Five-year relative survival is below 45% and, unlike other common cancer types, the proportion of women who die from their disease has not improved substantially over time. There are several well-established risk and protective factors for epithelial ovarian cancer; most relate Conflict of interest...
Epithelial ovarian cancer (OvCa) is associated with high mortality and, as the majority (>75%) of women with OvCa have metastatic disease at the time of diagnosis, rates of survival have not changed appreciably over 30 years. A mechanistic understandi