Epithelial–mesenchymal transition (EMT) is a process whereby tightly-interacting and immotile epithelial cells acquire the phenotype of loosely-adherent and motile mesenchymal cells. EMT not only facilitates morphogenesis during embryonic development but also promotes invasion and metastasis in tumors. ...
Epithelial-mesenchymal transition (EMT) is a complex process in which epithelial cells acquire the characteristics of invasive mesenchymal cells. EMT has been implicated in cancer progression and metastasis as well as the formation of many tissues and organs during development. Epithelial cells undergoing...
Epithelial–Mesenchymal Transition OriginofEpitheliumandMesenchyme •Therearetwomajortypesofcellarrangements intheembryo: •epithelialcells,whicharetightlyconnectedto oneanotherinsheetsortubes, •andmesenchymalcells,whichareunconnected tooneotherandoperateasindependentunits. OriginofEpitheliumandMesenchyme •Epithel...
摘要: Background information: Evidence has shown that mesenchymal-epithelial transition (MET) and epithelial-mesenchymal transition (EMT) are linked to stem cell properties. We currently... 查看全部>>关键词:EMT Immortalisation MET Oral epithelial cells Stem cell ...
In the kidney, a unique plasticity exists between epithelial and mesenchymal cells. During kidney development, the metanephric mesenchyme contributes to emerging epithelium of the nephron via mesenchymal to epithelial transition (MET). In the injured adult kidney, renal epithelia contribute to the ...
aenglish customs 英国风俗[translate] aheels over head 停顿在头顶上[translate] aIntestinal stem cells and epithelial-mesenchymal interactions in the crypt and stem cell niche. 小肠干细胞和上皮mesenchymal互作用在土窖和干细胞适当位置。[translate]
To explore whether interactions between normal epithelial and mesenchymal cells can modulate the extent of radiation-induced DNA damage in one or both types of cells. Human primary thyrocytes (PT), diploid fibroblasts BJ, MRC-5, and WI-38, normal human mammary epithelial cells (HMEC), and endot...
Furthermore, tumorigenesis and wound repair both depend on communication between epithelial cells, mesenchymal cells and bone marrow-derived cells. These studies suggest ways to harness stem cells for wound repair while minimizing cancer risk. This is a preview of subscription content, access via your...
Peritoneal fibrosis is the main reason leading to declining efficiency and ultrafiltration failure of peritoneum, which restricts the application of PD. It is believed that the Epithelial-Mesenchymal Transition (EMT) of peritoneal mesothelial cells is reversible and the beginning step of peritoneal ...
Interaction between epithelial cells and mesenchymal cells also occurs during the wound healing (Reviewed in refs 3,59). Since KY cultures contained a feeder layer consisting of mesenchymal cells, crosstalk between epithelial cells and mesenchymal cells via soluble factors may have occurred during the ...