Epilepsy vs. seizures Seizures are the main symptom of epilepsy. In fact, Johns Hopkins Medicine define epilepsy as having “two or more unprovoked seizures.” Some people may have a single seizure, or they may experience seizures that are not due to epilepsy. It is even possible for doctors...
The current definition of epilepsy allows diagnosis and treatment of epilepsy after a first seizure if the recurrence risk is >60%. We evaluate treatment decisions, seizure recurrence and risk factors for epilepsy related to the application of the new definition of epilepsy....
Pt. IDAge at MRI (years)GenderSeizures onset (years)Disease duration (years)Past seizures typesAEDSeizure-free > 1-year 1 26 F 12 14 A PB Yes 2 21 M 15 6 A; TC VPA Yes 3 22 F 15 7 A; TC; M LEV Yes 4 16 F 10 6 A VPA Yes 5 16 M 12 4 A; TC Drug-naive Yes 6 ...
The first stimulation produces a seizure with short duration and slight motor behaviors; however, over repeated stimulations, the seizures gradually become more prolonged and motor behaviors are intensified, culminating in intermittent generalized seizures (Bertram, 2007; Goddard et al., 1969; Racine, ...
Analysis of only those participants who provided complete data in year 2 (or reported seizures in year 2) showed that 0 of 19 in the medical group (0%) vs 11 of 13 in the surgical group (85%) were seizure free (OR=∞; 95% CI, 14.8 to ∞; P < .001). The sensitivity analysis...
seizure burden, medication load, and psychosocial challenges that medically-intractable patients often face. Notably, when split into short vs. long duration groups, patients with a longer disease duration also presented with topological regularization primarily in temporo-parietal cortices. This is in ...
Antiepileptic drugs (AEDs) are chosen based on seizure type and clinicians strive for maximum seizure control with minimum side ef- fects. The practicalities of certain treatment choices are very important in ASD. Factors such as available formulations (liquid vs. tablets vs. capsules), dosing ...
Twenty-five patients (16.9%) taking cannabidiol had at least a 75% reduction in seizures, vs none taking placebo (Figure 2B). One patient in the CBD25 group was seizure free during the full treatment period; 4 patients in the CBD25 group, 2 in the CBD50 group, and none in the ...
an epilepsy entity unclassifiable either as partial or generalized by all the clinical data including EEG findings; mental and motor dysfunction absent prior to seizure onset but appearing later; absence of epileptiform activities on EEG in the initial stage; stubborn refractoriness to conventional antiep...
Based on the operational definition of AED resistance in patients with epilepsy,16 the term “pharmacoresistant” applied in the context of animal models can be defined as persistent seizure activity not responding or with very poor response to monotherapy with at least two current AEDs at maximum...