Your epilepsy team can help you understand the risks and benefits of surgery so you can make the best decision that will help you control your seizures
The intracranial EEG is also a tool used for brain mapping, a process to determine the locations that regulate key functions to make sure they don't overlap with an area that will undergo surgery. "If we are going to resect [or remove] a certain part of the brain, we must ensure that...
In Switzerland, 80 to 100epilepsyoperations are done every year. Of these, 20-30% require an invasive presurgical phase in order to locate the region that will potentially be removed. The success rate of surgery is around 80%.
A meta-analysis of 21 studies involving almost 1,200 patients undergoing epilepsy surgery showed an overall rate of post-operative seizure freedom (Engel Class I outcome) of 45.1% [73]. One of the significant predictors of long-term seizure freedom was abnormal preoperative MRI (RR 1.64, 95% ...
temporal sclerosis [153], perhaps due to improved outcomes of childhood febrile seizures. At the same time, the outcomes of extratemporal epilepsies are improving with new diagnostic techniques. The mortality of surgery is around 0.1–0.5% [151], similar to the annual rate of SUDEP in ...
Epilepsy surgery has been tried in select cases of autoimmune epilepsy [105, 106]. However, among these patients, outcomes seem to be worse when compared with other etiologies of drug-resistant epilepsy. Outcome and Prognosis Most patients with autoimmune epilepsy and encephalitis are responsive to ...
When medication fails to control a person's seizures, surgery may be considered. If the abnormal electrical activity that triggers each seizure is coming from one particular part of the brain, cutting out that part of the brain can stop the repeated seizures. Of course this kind of brain ...
Epilepsy affects different people differently. The good news is that there are many forms of treatments available that can help a person control their episodes such as medications, surgery, dietary therapies, devices and other treatment approaches. ...
This proves extremely important in the field of epilepsy surgery, where precise localization of ictal onset is crucial to localizing the epileptogenic zone. In clinical practice it is often difficult to determine seizure focality without the use of EEG. Likewise, it is often ...
For the past 20 years, our group has been collecting tissues and performing multimodal analyses on human epileptic neocortex tissues to build highly integrated dataset that links clinical, electrical, imaging, histological, and molecular data from patients who underwent two-stage epilepsy surgery. This...