which is widely expressed in humans, and can be found in the mitochondria or cytoplasm. Its role is to bind PLP and ensure its availability for coenzymes, thus avoiding PLP reacting with other substrates or being phosphorylated by intracellular phosphatases [4]. Therefore, mutations ...
Nocturnal Frontal Lobe EpilepsyNocturnal frontal lobe epilepsy (NFLE) is a focal epilepsystarting in childhood and persisting into young adulthood.Affected individuals are typically of normal intelligence, butra... 查看全部>>NobiliL.ProserpioP.CombiR.ProviniF.PlazziG....
Even if folic acid supplementation is commenced in adulthood, it can still help reduce the frequency of seizures and improve the patient's quality of life. The combination of oral folic acid with intravenous administration is considered more effective than oral administration alone [110]. However, ...
There is no known genetic basis shared between epilepsy and antisocial behaviour; and although epilepsy starting early in life probably imposes a disadvantage which could predispose to antisocial behaviour, a surprising proportion of our sample developed epilepsy well into adulthood. In the general popula...
Epileptic seizures appearing in adulthood are not uncommon. They are usually provoked or involve acute symptoms, but late-onset unprovoked seizures are also frequent. The chance of repeated seizures is high, and when they occur late-onset epilepsy (LOE) is diagnosed. The incidence of LOE, partic...
in adulthood may be expected. A positive response to antiepileptic drugs (e.g.,carbamazepine, topiramate) is reported in most cases. However, more than one-third of patients, particularly those with more complex forms, are resistant to antiepileptic medications. Surgery may be a choice in very ...
A tri-phasic distribution of epilepsy in DS is now generally accepted and includes: infancy epilepsy, early adulthood epilepsy, and a distinct epilepsy syndrome in patients over 50-55 years (Johannsen et al., 1996; Moller et al., 2002). Seizure onset is reported to occur within a ye...
Epilepsyrefers to a pattern of chronic seizures of any type over a long period. Thirty percent of children diagnosed with epilepsycontinue to have repeated seizures into adulthood, while others improve over time. What Are Types, Symptoms, and Signs of Seizures in Children?
23 In addition, these children outgrow the epilepsy, and the interictal EEG abnormality resolves during their teenage years.24 That the seizures remit and the rate of epilepsy in these children in adulthood is no greater than that in the general population24 is in contrast to the adage that ...
Association between socioeconomic status and the development of mental and physical health conditions in adulthood: a multi-cohort study Lancet Public Health, 5 (2020), pp. e140-e149 View PDFView articleView in ScopusGoogle Scholar [72] S.V. Katikireddi, K. Skivington, A.H. Leyland, K. ...