(1) Excess of Excaitatory ( acetylecholine- or Glutamate –related activity ) (2) Decreased inhibitory ( GABA –related activity) Together and/or (2) above leading to instability of cell-membrane & lowered threshold for exciatation excessive polarization, hypopolarization allowing the ...
(2) Decreased inhibitory ( GABA –related activity) Together and/or (2) above leading to instability of cell-membrane & lowered threshold for exciatation excessive polarization, hypopolarization allowing the cell to be more susceptible to activation spontaneously or by any ionic imbalances ...