We argue that kindling of epilepsy occurs due to the formation of a large number of excitatory synaptic connections through a Hebbian learning mechanism. Several experimentally observed phenomena, such as the initial rapid growth and eventual saturation of the amplitude and duration of the after...
aEpilepsy is what we usually call the epilepsy disease, is a chronic brain disease, this disease occurs, will be harm to people is very large, the people hurt will be very big, therefore, we need to understand this kind of disease 癫痫症是什么我们通常称癫痫症疾病,是一种慢性脑子疾病,这种...
Traumatic brain injury usually occurs due to a number of causes such as traffic accidents or work accidents. Within 1 to 2 days, brain damage can trigger inflammatory reactions, attack and damage nerve cells and leave permanent scarring in the brain. This leads to a change in the concentration...
Pure epilepsies due to single gene disorders B. Symptomatic B. Pure epilepsies with complex inheritance C. Cryptogenic II. Generalized II. Symptomatic/structural–metabolic A. Idiopathic A. Predominantly genetic or developmental B. Symptomatic or cryptogenic B. Predominantly acquired C. Symptomatic ...
Due to its complex and multifaceted nature, developing effective treatments for epilepsy is still a major challenge. To deal with this complexity we introduce the concept of degeneracy to the field of epilepsy research: the ability of disparate elements to cause an analogous function or malfunction....
in utero exposure to ASMs. This lack of knowledge can cast a shadow of uncertainty over their reproductive journey, forcing too many women to make the difficult choice between managing their epilepsy and planning for a family, with some women deciding against having a family due to the ...
6 In contrast, SUDEP most commonly occurs at older ages, after longer duration of epilepsy. Sillanpaa noted that epilepsy-related deaths in “uncomplicated” epilepsy were predominantly due to SUDEP and occurred primarily in adolescence and adulthood.8 In the combined cohort Sudden unexpected death ...
Contusions, hemorrhages and blood deficiency can also lead to partial softening of brain tissue, closed brain trauma around 5% occurs in adult epilepsy, severe acute and open brain injury epilepsy occurs mo 精神创伤是其中一癫痫症,脑子诞生精神创伤的起因是初期根据症状的癫痫症的同道会。 挫伤、出血和...
Due to data sharing restrictions and with the Epi25 cohort data located in the USA and the other cohorts located in the European Union, we were unable to merge the data or use the same imputation server. Postimputation QC was largely similar among all cohorts. The Epi25 cohort used an in...
Multimorbidity is an emerging priority in healthcare due to associations with the ageing population, frailty, polypharmacy, health and social care demands. It affects 60–70% of adults and 80% of children with epilepsy. Neurodevelopmental conditions are commonly seen in children with epilepsy, while...