We argue that kindling of epilepsy occurs due to the formation of a large number of excitatory synaptic connections through a Hebbian learning mechanism. Several experimentally observed phenomena, such as the initial rapid growth and eventual saturation of the amplitude and duration of the after...
Also known as Encephalotrigeminal Angiomatosis, this rare condition is due to a mutation of the GNAQ gene in both males and females. For more information, visit the Epilepsy Foundation online
Traumatic brain injury usually occurs due to a number of causes such as traffic accidents or work accidents. Within 1 to 2 days, brain damage can trigger inflammatory reactions, attack and damage nerve cells and leave permanent scarring in the brain. This leads to a change in the concentration...
Seizures, abnormal movements or behavior due to unusual electrical activity in thebrain, are a symptom of epilepsy. But not all people who appear to have seizures haveepilepsy, a group of related disorders characterized by a tendency forrecurrentseizures. Non-epileptic seizures(called pseudoseizures) ...
Stroke is the most common cause of acquired epilepsy. The pathogenesis of epilepsy after stroke has been studied in depth, with some mechanisms confirmed while others being new hypotheses that awaits confirmation. Currently, it is widely accepted that epilepsy occurs after stroke due to the imbalance...
The reason that Epilepsy has been misunderstood has been mainly due to research not being conducted until the middle of the nineteenth century. There are six main types of seizures and many treatments that can assist an epileptic patient. Many facts and myths exist about a person who has ...
(BBB) breakdown in DM might plays a role in epileptogenesis. As increasedBBBpermeability might leads to the invasion of pro-inflammatory cytokines into the brain [44]. Inflammation occurs in the CNS due to leaky BBB which can further initiates epileptogenesis as well as induction of epileptic...
due to research not being conducted until the middle of the nineteenth century. There are six main types of seizures and many treatments that can assist an epileptic patient. Many facts and myths exist about a person who has Epilepsy, which, is why it is an important disorder to understand....
Epilepsy occurs due to significant damage or structural differences in the brain. Multiple factors may contribute to its development. These factors can include: brain damage from birth or birth-related causes, such as low birth weight genetic conditions and syndromes structural or functional differences...
This occurs primarily due to post-translational modifications of receptor channels such as phosphorylation of the NR2A/B subunits of the NMDA receptor, and subsequent increase in calcium influx which may lead to neuronal hyperexcitability and cell death [90]. In addition, increased glutamate discharge...