During acute, silent and chronic phases of epilepsy, the expression of hippocampal kainate glutamate receptor (GluK2) and the GABAA receptor alpha1 subunit (GABAAR-alpha1) was up-regulated and down-regulated, respectively. Resveratrol reversed these effects and induced an antiepileptic effect. Further...
There are five different kinds of KCNQ potassium channels in the body, but only two are important in epilepsy and tinnitus: KCNQ2 and KCNQ3. The problem with retigabine is that it acts on other KCNQ potassium channels as well. That's why it has so many unwanted side effects. Tzingounis ...
The behaviour and cognition of epilepsy patients may be affected by several factors including the location of the seizure foci in the brain, seizure type or duration of epilepsy. A potential way to investigate the effects of epilepsy on behaviour, cognition and perception is to compare the perform...
There are five different kinds of KCNQ potassium channels in the body, but only two are important in epilepsy and tinnitus: KCNQ2 and KCNQ3. The problem with retigabine is that it acts on other KCNQ potassium channels as well. That's why it has so many unwanted side effects. Tzingounis ...
Neuroprotective effects of naltrexone in a mouse model of post-traumatic seizures Saul Rodriguez , Shaunik Sharma & Alexander G. Bassuk Article 24 May 2024 | Open Access A novel hepatocyte ketone production assay to help the selection of nutrients for the ketogenic diet treatment of epileps...
1. Stimulation of the rostral-ventromedial pole of the cerebellar fastigial nucleus exerts powerful effects on systemic and cerebral circulation. 2. Excita... EV Golanov,P Zhou - 《Cellular & Molecular Neurobiology》 被引量: 181发表: 2003年 A Portable Wireless Online Closed-Loop Seizure Controller...
but no direct proof connectingoxidative stressand innate immune system activation with epilepsy. Moreover, approximately one-third of epilepsy patients do not respond well to currently available therapies, and two-thirds of patients have adverse side effects to the medications, according to the study'...
Sun HL, Zhu W, Zhang YR, Pan XH, Zhang JR, Chen XM,et al. Altered glutamate metabolism contributes to antiepileptogenic effects in the progression from focal seizure to generalized seizure by low-frequency stimulation in the ventral hippocampus. Epilepsy Behav 2017, 68: 1–7. ...
"If your seizures aren't under control, see anepilepsyspecialist," Kapur said. "Your goal should be no seizures and no side effects." More information:The American Epilepsy Society has more information onhow to manage seizures. Copyright © 2021HealthDay. All rights reserved....
The occurrence of hypoxic brain regions, as usually occurs in the core of brain tumors, is associated with changes in gene expression with negative effects on the stability of DNA repair mechanisms and on the likelihood of mutations. Under these conditions, the astrocytic cell membrane becomes ...