Epigenetics refers to the heritable, but reversible, regulation of gene expression mediated principally through changes in DNA methylation and chromatin organization. In this chapter we reinterpret a series of epidemiological, clinical, and molecular findings in major psychosis within the framework of ...
Epigenetics refers to the establishment of heritable changes in gene expression without alterations in primary DNA sequences. Such gene patterns play an essential role in various biological processes including embryonic developmental events, adult cell renewal, gene imprinting, and X-chromosome inactivation...
Epigenetics refers to the way in which the environment in the wide sense participates in the regulation of gene expression. Several studies show that the well-known beneficial role of a healthy lifestyle over a number of pathologies or as a pre-emptive therapy is at least in part exerted ...
Epigenetics refers to the study of the biological processes that regulate gene activity during our lifetime, and the array of factors that can impact it. Think of epigenetic processes as collections of chemical “tags” that regulate where, when, and to what extent genes are activated or ...
Epigenetics refers to the heritable change in gene expression that does not involve changes to the underlying DNA sequence. DNA methylation, histone modifications and non-coding RNAs (ncRNA) play fundamental roles in epigenetic regulation. The study of epigenetic modifications of the Cancer cell genome...
A comprehensive understanding of transcription factors and the mechanisms that alter their activity is a fundamental goal of modern life science research.\nEpigenetics refers to the packaging and accessibility of the genome in each of the trillions of cells in our bodies. The prefix "epi" (meaning...
Mitochondrial epigenetics (or mitoepigenetics) refers to the study of epigenetic modulation in the mitochondria, which can contribute to phenotypic plasticity1,2. Mitoepigenetic mechanisms include mitochondrial DNA (mtDNA) methylation, non-coding RNAs, post-transcriptional modifications of mitochondrial RNAs ...
Epigenetics refers to heritable changes in gene expression that do not alter the DNA sequence. These changes are driven by mechanisms such asDNA methylation,histone modifications, andnon-coding RNA interactions, which regulate gene activity. Influenced by environmental and lifestyle factors, epi...
Theterm‘‘epigenetics’’referstoheritablechangesingeneexpression,whicharenotaresultofchangesintheDNAsequence,butratherduetoalterationsrelatedtothepackaging(therebyalteringDNAaccessibility)and/ortranslationofgeneticinformation. Startingfromthemid-1990s’,therehasbeenasteadygrowthinthenumberoflaboratoriesandinvestigatorsin...
Epistasis involves interactions between different genes affecting a trait, whereas epigenetics refers to changes in gene expression not involving alterations to the DNA sequence.