Green tea is one of those natural products that contains bioactive components like epigallocatechin-3-gallate (EGCG), a flavanol, that has been widely studied and proven for their health benefits. EGCG also demonstrated as antioxidant, antiaging, antitumorigenic, antidiabetic, antileukemic, anti-...
These results provide a novel mechanism involving ERs through which low doses of EGCG exerted benefits to sperm physiology, also detected data evidence the adverse action of high EGCG concentrations probably related to its prooxidant and antiestrogenic potential.doi:10.1002/mnfr.201200190...
This study provides strong evidence supporting the benefits of using EGCG to treat cisplatin ototoxicity. We show that EGCG protects against cell damage and apoptosis in multiple regions of the cochlea, such as OHCs, SV and SL. Protection was also observed at the level of IHC ribbon synapses, ...
Epigallocatechin gallate(EGCG), also known as epigallocatechin-3-gallate, is the main activecatechinin green tea which belongs to the subgroup offlavanolsof the flavonoids family.EGCGis linked to the majority of health benefits in various diseases such as obesity, diabetes, stroke, Parkinson and ca...
of EGCG in treating diabetes, cancer, neurodegenera- tive disorders, cardiovascular disease and obesity.28–31 Our interest in EGCG stems from the fact that it provides an orally effective STAT1 inhibitor with anticancer properties, which could complement the overall therapeutic benefits of cisplatin...
Green tea possesses multiple physiological and pharmacological benefits, including anti-inflammatory and antioxidant effects, prevention of obesity, diabetes, cancer, and other diseases [22, 23]. The major active ingredient in green tea is epigallocatechin-3-gallate (EGCG), a potent antioxidant that ca...
Previous studies have shown that consumption of green tea has benefits for treating human diseases, such as Parkinson's disease and cancer.27–29 The major flavonoids of green tea extracts are catechins, including epica- techin (EC), epigallocatechin (EGC), epicatechin-3-gallate (ECG) and EGCG...
Many health claims have been made about the medicinal benefits of drinking green tea, including neuroprotection. This study mainly focuses on Epigallocatechin 3-gallate (EGCG), a potent antioxidant, which is abundantly found in green tea. Cadmium [Cd2+] is a toxic pollutant that leads to neurotox...
Epidemiological studies suggest that the beneficial cardiovascular health effects of diets rich in green tea are, in part, mediated by their flavonoid content, with particular benefits provided by members of this family such as epigallocatechin gallate (EGCG). Although their bioavailability is discussed,...
Curcumin and epigallocatechin gallate inhibit the cancer stem cell phenotype via down-regulation of STAT3-NFκB signaling Anticancer Res (2015)View more references Cited by (24) Health Benefits of Flavonoids 2019, Bioactive Compounds: Health Benefits and Potential Applications Show abstract Health Benefits...