Biochimica et Biophysica Acta (BBA) - Gene Regulatory MechanismsJournal2020,Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms SatoshiTakahashi,AkihikoYokoyama 4.3MLL/HAT hybrid complex (p300/CBP and its interactors) MLL fusions with a HAT form an MLL/HAT hybrid complex to cause leukem...
After utilizing whole-exome sequencing, we combined the defined EP300 gene mutation status with the nCRT response to analyze the influence of EP300 mutation on the nCRT response and immune microenvironment. Method and materials Patients The research was approved by the Institutional Review Board of...
These enzymes of opposite functions form a regulatory loop that controls gene expression. Acetylation of histones H3 and H4 coexists frequently with trimethylation of H3K4 at the promoter and TSS of transcriptionally active genes, as H3K4me3 promotes downstream H3/H4 acetylation by the recruitment of ...
including mammals such as primates (e.g. humans) and rodents (e.g., mice and rats), unless otherwise indicated. The term encompasses “full-length,” unprocessed CBP as well as any form of CBP that results from processing in the cell. The term also encompasses...
Check access to the full text by signing in through your organization. Access through your organization Section snippets Bioinformatics analysis From the Gene Expression Profiling Interactive Analysis (GEPIA) database, RNA expression information for cervical squamous cell carcinoma (CESC) and endocervica...