37, No. 6, 553-558, December 2005 The association of eotaxin-2 and eotaxin-3 gene polymorphisms in a Korean population with ulcerative colitis Young-Ran Park1,5, Suck-Chei Choi2, Soo-Teik Lee4, Kyung-Suk Kim5, Soo-Cheon Chae1,6 and Hun-Taeg Chung1,3 1Genome Research Center for ...
The natural form of dendritic cell-derived chemokine 1 (CCL18) inhibits CCR3 (17), although less strongly than an N-terminal alanine to methionine mutant (14). A thorough pharmacological characterization of CCR5 characterized MCP-3 (CCL7), a promiscuous agonist for CCR1, -2, and -3, as ...
Eotaxin-3/CCL26 is a functional ligand for CCR3 and abundantly produced by IL-4-/IL-13-stimulated vascular endothelial cells. CCL26 also functions as a natural antagonist for CCR1, CCR2, and CCR5. In this study, we report that CCL26 is yet a functional ligand for CX3CR1, the recepto...
To identify novel molecules involved in the IL-4-dependent eosinophil extravasation, cDNA prepared from HUVEC stimulated with IL-4 was subjected to differential display analysis, which revealed a novel CC chemokine designated as eotaxin-3. The human eotaxin-3 gene has been localized to chromosome 7...
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支气管哮喘小鼠肺组织eotaxin/CCR3路径表达上调及地塞米松对其的抑制作用 起到重 要作用.本研究中以卵白蛋白(OVA)致敏和激发的过敏性哮喘小鼠模型为平台,揭示eotaxin/CCR3路径在哮喘发病过程中的重要作用以及地塞米松 (DXM)对该路径的... 徐峰,沈华浩,黄华琼,... - 中华医学会全国哮喘学术会议暨中国哮喘联盟大会 ...
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Cooperation between interleukin-5 and the chemokine eotaxin to induce eosinophil accumulation in vivo. Experiments were designed to study the effect of systemically administered IL-5 on local eosinophil accumulation induced by the intradermal injection of th......
We postulate that expression of CCR3 may underlie situations where both DCs and eosinophils accumulate in vivo, such as the lesions of patients with Langerhans cell granulomatosis. 展开 关键词: Humans Dendritic Cells Monocytes Bone Marrow Cells Cells, Cultured Cell Line Chemokines, CC Receptors, ...
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