This article focuses on the activation of eosinophil effector functions in response to different CC chemokines.doi:10.1016/S0926-9959(98)94568-8J. ElsnerA. KappJournal of the European Academy of Dermatology & Venereology
What Do the Results Mean? Eosinophils make up 0.0 to 6.0 percent of your blood. The absolute count is the percentage of eosinophils multiplied by your white blood cell count. The count may range a bit between different laboratories, but a normal range is usually between 30 and 350. A count...
It is localized to the matrix of the secondary granule of the eosinophil (49) and is also known as RNase-2, nonsecretory RNase, and RNase-Us, the latter based on its specificity toward uridine-containing nucleotides. EDN is one of the most abundant RNases in humans and has been isolated...
In addition, RhoH appears to promote cellular quiescence in a manner similar to what has been reported for GATA-2.10 Furthermore, our data suggest that IL-5 induces RhoH in immature eosinophils, a pathway that also remains functional following maturation. Taken together, our data suggest that ...
observed changes in segmented filamentous bacteria and Bacteroidetes that were in the opposite direction of what we observed.39 The reasons for this difference are unclear, but both studies are consistent with a dominant role for eosinophils in regulating intestinal commensal microbiota. We propose that...
The physiological function of the granule contained cytotoxic ribonuclease Eosinophils contain a large amount of ECP but the ques- tion is why? What is the function of this protein? There is a constitutive baseline level of the eosinophils in many tis- sues and certain stimuli cause elevated ...
It is expected that the number of asthma patients worldwide will exceed 300 million by 2025. The asthma mortality rate is between 1.6 and 36.7 per 100,000, with the highest incidence among children. The asthma incidence of children aged 13–14 years is 0–30% [60]. There are about 30 ...
[7, 12] While the reasons for this apparent disparity are not clear, it is possible that local montelukast metabolism (i.e. in the small intestine) may vary as a consequence of disease state. Nonetheless, what remains to be determined is whether there is a link between systemic and tissue...
(Demarche et al., 2016). What's more, the peripheral eosinophil count is the only predictor of frequent exacerbations in patients with mild asthma and never smoking adults with severe asthma (Pavord et al., 2020; Westerhof et al., 2016). After exposure to allergens,eosinophilscould be ...
Asthma in children and adults-what are the differences and what can they tell us about asthma? Front Pediatr, 7 (2019), p. 256 View in ScopusGoogle Scholar 27 J. Sánchez, A. Sánchez, R. Cardona Clinical characterization of patients with chronic spontaneous urticaria according to anti-TPO ...