These cells are lineage negative, meaning that they fail to express mature lymphocyte markers such as CD3, CD14, CD16, CD19, CD20 and CD56, but express high levels of stem cell markers such as CD117 (c-Kit). These cells are a small fraction of the total cell population in a given ...
Eosinophilia, typically defined as an absolute eosinophil count (AEC) of ≥ 450 cells/μL, in immigrants and refugees from locations throughout the world is most often caused by helminthic infections.75 Measuring the AEC of immigrants can add considerable ability to detect asymptomatic infections. ...
In eosinophilic asthma an increased eosinophil cell count in peripheral blood is the gold standard for determination of the pheno-/endotype and severity of disease. Despite a broad consensus there is concern on validity of this simple measurement, because the eosinophil compartment is far from ...