The structure and function of the MCR activation complex fromMethanococcus maripaludiswere revealed, demonstrating its ATP-dependent ability to activate MCR and form methane while uncovering a unique electron transfer pathway involving iron–sulfur clusters similar to the nitrogenase cofactor intermediates. ...
Denaturation is changing the structure of an enzyme (or other protein) so it can no longer carry out its function. 3.6.5 Explain the use of lactase in the production of lactose-free milk. Lactose is the sugar found in milk. It can be broken down by the enzyme lactase into glucose and...
Here, we report the isolation and characterization of two CYP450 enzymes, SbCYP82D1.1 and SbCYP82D2, which function as the flavone 6-hydroxylase (F6H) and flavone 8-hydroxylase (F8H), respectively, inS.baicalensis. SbCYP82D1.1 has broad substrate specificity for flavones such as chrysin ...
However, enzymes, even if not completely restricted to the CNS, may be responsible for a specific function in the nervous system, i.e., in generation and propagation of electric impulses. An enzyme that illustrates these points may be ATP:pyridoxal 5-phosphotransferase (2.7.1.35), which is ...
“basic canyon” on the cullin subunit of an SCF complex, helping to position the E2 near the RING subunit while allowing for rapid association and turnover in chain building44. In these E2s, the aforementioned short insertion, termed the acidic loop, affects function in several ways. First,...
Metabolism - DNA Synthesis, Enzymes, Energy: The maintenance of genetic integrity demands not only that enzymes exist for the synthesis of DNA but that they function so as to ensure the replication of the genetic information (encoded in the DNA to be cop
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Hochstrasser M: Evolution and function of ubiquitin-like protein-conjugation systems. Nat Cell Biol. 2000, 2: E153-E157. 10.1038/35019643. CAS PubMed Google Scholar Bohnsack RN, Haas AL: Conservation in the mechanism of Nedd8 activation by the human AppBp1-Uba3 heterodimer. J Biol Chem. 20...
We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media. By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some...
We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media. By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some...