Lisi GP, Loria JP (2016) Using NMR spectroscopy to elucidate the role of molecular motions in enzyme function. Prog NMR Spec- trosc 92-93:1-17Lisi, G.P., and Loria, J.P. (2016). Using NMR spectroscopy to elucidate the role of molecular motions in enzyme function. Prog. Nucl. Magn...
Compensatory and Long-Range Changes in Picosecond–Nanosecond Main-Chain Dynamics upon Complex Formation: 15N Relaxation Analysis of the Free and Bound Sta... Mapping of the Rac1 GTPase surface that contacts the Rho GTPase binding domain of plexin-B1 by solution NMR spectroscopy confirms the plexin...
et al. Coherent multidimensional optical probes for electron correlations and exciton dynamics: from NMR to X-rays. Acc. Chem. Res. 42, 553–562 (2009). A review of multidimensional spectroscopy techniques with an outlook to future XFEL applications. Article MathSciNet Google Scholar Schweigert...
coherently due to their pronounced disorder. The conformational variations of loop regions become evident in NMR structural ensembles, which show a multitude of different conformations for the same loop. The high mobility of loops has been frequently confirmed by trajectories of molecular dynamics ...
V. AlphaFold 2 and NMR spectroscopy: partners to understand protein structure, dynamics and function. Front. Mol. Biosci. 9, 906437 (2022). Article CAS PubMed PubMed Central Google Scholar Yang, J., Wang, Y. & Zhang, Y. ResQ: an approach to unified estimation of B-factor and ...
The unique activation mode of the boron enzyme was confirmed using X-ray crystallography, high-resolution mass spectrometry (HRMS) and 11B NMR spectroscopy. Our study demonstrates that genetic-code expansion can be used to create evolvable enantioselective enzymes that rely on xenobiotic catalytic ...
Single molecule spectroscopy is a unique tool for probing conformational dynamics and reaction kinetics o... J Shi 被引量: 0发表: 2006年 Preliminary Studies of Enzyme Kinetics on Esterase Activity of DNA Based on the discovering enzymatic activity of esterase from mang bean, chinese spider and ...
. The findings have been possible through an integrative structural biology approach where we utilize state-of-the-art quantitative 19F NMR spectroscopy (relaxation dispersions) for determination of microscopic rate-constants for conformational dynamics of a large (69 kDa) assembly....
A similar important development is the structural genomics initiative, which has four key aims: to organize known protein sequences into families; to select family representatives as targets; to solve the three-dimensional structure of targets by X-ray crystallography or NMR spectroscopy; and to ...
31P NMR spectroscopy is thus an important probe of structure, dynamics and mechanism in native and site-directed mutations of PLP-dependent enzymes. Examples of all of the above are provided in this review. This article is part of a Special Issue entitled: Pyridoxal Phospate Enzymology....