环境DNA(eDNA) 是生物体在生长活动时,存在于体内细胞、组织、血液或者体外粪便、尿液等释放到环境中的DNA。eDNA可以被用作代替传统刺网法的一种监测工具,且监测数据更准确。水样eDNA最常用的两种监测方法是:1、实时荧光定量多聚核苷酸链式反应(qPCR)以检测和估计目标物种的数量;2、宏条形码,包括使用针对分类群的“通...
该研究在长江入海口与黄海沿岸比较评估了常规主动过滤法和课题组自主研发的被动采样器(PEDS)采集环境DNA(eDNA)对鱼类多样性和濒危物种长江江豚的检测效果。eDNA宏条形码(metabarcoding)分析显示两种采样方法捕获了相当的物种丰富度和相似的群落结构,...
DNA diagenesis : effect of environment and time on human bone[ J ]. Ancient Biomolecules, 2002,4: 1--7.Rollo F ,Ubaldi M ,Marota I et al . DNA diagenesis :effect of environment and time on human bone[J ] . Ancient Biomolecules ,2002 , 4 :1 --7....
Gene–environment interactions have been studied by a candidate-gene approach focusing on metabolism, DNA repair, and apoptosis. Here, we review the influence of gene–environment interactions in carcinogenesis, with emphasis on heavy metal and pesticide exposures....
Gene-environment interactions Germline genetic variation DNA sequence Single nucleotide polymorphisms (SNPs Somatic mutation Pharmacogenomics Pharmacogenetics Genome-wide association study GWAS Epigenetic alterations DOI: 10.1007/978-1-4471-6678-8_10 被
DNA was obtained from 377 adolescents, representing the four quadrants of high or low depression and high or low environmental risk. Markers within, or close to, each of the serotonergic genes 5HTT, HTR2A, HTR2C, MAOA (monoamine oxidase type A) and tryptophan hydroxylase (TPH) were ...
A difficult problem concerning the interaction of DNA with amphiphiles of opposite charge above their critical micelle concentration is the propensity for aggregation of the condensed DNA complexes. In this study, this problem was addressed by attenuating amphiphile charge density within a cholate micelle...
Gene-environment interaction involved in oral carcinogenesis: molecular epidemiological study for metabolic and DNA repair gene polymorphisms. Background: Exposure to environmental carcinogens leads to oral squamous cell carcinoma (OSCC); however, the impact of genetic variations in carcinogen met... T Su...
as these effects result from dynamic social circumstances that are part of a true causal chain in between our DNA and complex mental and physical health outcomes. Statistical models, research designs and conclusions of GWASs need to more carefully reflect the reality of the social and geographic ...
(v2.r644)62using the HapMap genetic maps. Coancestry matrices were obtained from ChromoPainter with parameters estimation step done with ten iterations on four chromosomes only. ChromoPainter method performs a reconstruction of every individual genome using chunks of DNA donated by the other ...