Moore JP,Doms RW.The entry of entry inhibitors: a fusion of science and medicine. Proceedings of the National Academy of Sciences of the United States of America . 2003Moore, J.P. and Doms, R.W. (2003). The entry of entry inhibitors: a fusion of science and medicine. Proc. Natl. ...
Mark A.Wainberg,Gerasimos J.Zaharatos, inSande's HIV/AIDS Medicine, 2012 Fusion and Entry Inhibitors A singlefusion inhibitorand a singleentry inhibitorhave been approved for use in clinical practice. The fusion inhibitor is thepolypeptideenfuvirtide(ENF), which is administered subcutaneously. The ...
Inhibition of virus entry has become a major concept in the development of new antiviral drugs. Entry inhibitors can either neutralize activities of viral surface proteins or target essential host factors such as (co)receptors. Due to its distinct tissue tropism and the highly specific viral and ...
Topical application of entry inhibitors as "virustats" to prevent sexual transmission of HIV infection With the continuing march of the AIDS epidemic and little hope for an effective vaccine in the near future, work to develop a topical strategy to prevent H... MM Lederman,R Jump,HA Pilch-...
© 2002 by The McGraw-Hill Companies, Inc. PC Abbreviation for Pneumocystis carinii. Medical Dictionary for the Health Professions and Nursing © Farlex 2012 PC Abbrev. for Pharmaceutical Chemist. Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005...
Faculty of Medicine and Health Sciences, Discipline of Immunology and Microbiology, Australia Kenneth W. Beagley & Christine M. Gockel Department of Biological Sciences, The University of Newcastle, Newcastle, Australia Nicole Newcombe, Zhong Ling Wu & Russell C. Jones ...
Moreover, the proteins in endolysosomal calcium channels, TPC1 and TPC2, recently have been identified as key players in Ebola entry. The inhibitors for TPCs can block nicotinic acid adenine dinucleotide phosphate (NAADP)-stimulated calcium outflow and Ebola infection47. The sphingosine treatment ...
Idemyor V. Human immunodeficiency virus (HIV) entry inhibitors (CCR5 specific blockers) in development: are they the next novel therapies? HIV Clin ... Idemyor,Vincent - 《Hiv Clinical Trials》 被引量: 18发表: 2005年 Potent Inhibition of HIV-1 Infectivity in Macrophages and Lymphocytes by...
HIV-1 entry inhibitors: Evading the issue HIV-1 entry into cells is an attractive target for new antiviral agents. But will inhibitors aimed at the CCR5 co-receptor force HIV-1 to evolve more virul... NL Michael,JP Moore - 《Nature Medicine》 被引量: 245发表: 1999年 HIV-1 entry ...
entry inhibitors complement these gains by fighting COVID-19 in the unvaccinated population and the vaccinated who develop breakthrough infections. Moreover, the use of antibody cocktails and other viral entry inhibitors is also showing potential in combating new variants and other coronavirus clades. ...