In one version of this mechanism, water is “pushed out” by the enol form of the addition product. Simultaneous formation of C-O (pi) and migration of C-C (pi) in what can be called a “1,4-elimination” or “conjugate elimination” step. There are other ways to show this occurrin...
@Carbenoid: A year has passed since you requested a mechanism from @Mithoron. The statutes of limitation have run out. Your comment about why not do an aldol condensation (in base) is well taken. But the question was what is the structure of compound A. I have no problem wi...
Ketoandenoltautomers酮和烯醇互变异构体 Chapter13 α-SubstitutionandCondensationsofEnolsandEnolate Text1:Chapter22,p1003-1056Text2:11,13章 13.1Enolsandenolateions（烯醇和烯醇负离子）OHB:O - O H HB HO+B Resonance-stabilizedanionKetoform(酮式，Stable)烯醇阴离子，Enolateion OHH+HOHHOH-H+ Enol...
Equilibration results in the selective production of the thermodynamically more stable 2. As a side reaction, the counter anion, Tf2N−, could attack the silicon atom of 2 to produce silyl triflic imide (R3SiNTf2) [8–12] and the corresponding ketone 3. Therefore, the use of a large ...
(0) complex, leading to carboradicals formation via the C–O bond fragmentation. In this work, the radical mechanism was scrutinized by using TEMPO as radical trap. When the “3a+6c” reaction was performed in the presence of TEMPO (2.0 equiv), the7cformation was completed suppressed with ...
Quantum mechanical calculations have shown the barrier to intramolecular rearrangement in the keto-enol tautomerism to be prohibitively high. Instead, the 1-3 proton shift is seen to proceed much more economically via intermolecular pathways, notably via acid and base catalysis. The reaction profiles ...
Trichothecenemycotoxins, such asDONand T-2, HT-2, andDAS, have all been associated withGI diseasein animals. The primary mechanism of action of these mycotoxins involves the inhibition of protein synthesis. Vomitoxin or DON produced byFusariumgraminearumis the most prevalent of these secondary funga...
ChemInform Abstract: A QUANTUM MECHANICAL STUDY OF THE MECHANISM OF THE ENOL‐KETONE TAUTOMERISMchemical equilibria, complexation equilibriadoi:10.1002/chin.198017089G. KLOPMANP. ANDREOZZIJohn Wiley & Sons, LtdChemischer Informationsdienst
A quantum mechanical study of the mechanism of the enol-ketone tautomerismdoi:10.1002/bscb.19790881107G. KlopmanP. AndreozziWiley‐VCH Verlag GmbH & Co. KGaA
The reaction was slow and gave better results (with respect to the purity of the compounds). The synthesis began with the formation of a ketone enolate nucleophile in cool conditions (0 ˝C). AftMeorlecaudleds 2in01g5, t2h0,epaagpe–ppraogpe riate heterocyclic carboxylate, the ...