Racial and ethnic diversity among clinical trial participants is important to support science-driven strategies aimed at understanding the needs of those who are affected by the disease or condition being investigated. How can the biopharma industry achi
In today’s fast-paced medical landscape, the call for diversity in clinical trials resonates louder than ever. It’s not merely an option but a moral and scientific obligation essential for providing inclusive healthcare. As we move through the 21st century, the importance of medical treatments...
lowering the CrCL cutpoint from 50 to to 37 mL/min could be expected to improve representativeness for older patients (LD: 66% to 80%, the lower bound for representativeness).Conclusions:It is important to consider the complex nature of diversity when designing trials to ensure that optimizing...
Trials(2024) Use of mobile diagnostics and digital clinical trials in cardiology Sinje Gehr Nandha Kumar Balasubramaniam Christoph Russmann Nature Medicine(2023) Does clinical research account for diversity in deploying digital health technologies?
There has been a growing push to involve patients in clinical research, shifting from conducting research on, about, or for them to conducting it with them. Two arguments advocate for this approach, known as Patient and Public Involvement (PPI): to impro
This study addresses the critical challenge of detecting brain tumors using MRI images, a pivotal task in medical diagnostics that demands high accuracy and interpretability. While deep learning has shown remarkable success in medical image analysis, the
To address the heteroduplex formation, we reduced PCR cycles as has been previously suggested26,27,28,29,30from 28 to 15 cycles. As the diversity greatly varies among libraries, it should be noted that, this step requires to be optimized based on the nature of the library used. The reduc...
The findings provide a basis for a maturity model that may guide change to increase participation of ethnically diverse communities in PREMs. In the short-medium term, health systems and services must be able to recognise and respond to cultural and linguistic diversity in the population when appl...
In addition to the decline in Chao index and Shannon index of plac-hlyE group, the α-diversity in the SynCons and 5-FU was considerable with Ctrl group (Fig. 6a). The administration of either a single EcN strain or SynCons significantly enhanced the relative abundance of Escherichia, ...
in how light therapy works. As a result, the application of light therapy in wound treatment has been established [54]. Light therapy uses low-power light to illuminate the injured area without invasion to stimulate the body’s healing potential, promising a positive trajectory for clinical ...