Liver fibrosisHyaluronic acidMetalloproteinasesBackground: The Enhanced Liver Fibrosis (ELF) is a serological score that includes hyaluronic acid (HA), tissue inhibitor of matrix metalloproteinases-1(TIMP-1), and aminoterminal propeptide of type III procollagen (PIIINP) and shows good performance for ...
Enhanced Liver Fibrosis (ELF™). Package insert. Siemens Healthcare Diagnostics Inc; 2022. Cusi K, Isaacs S, Barb D, et al. American Association of Clinical Endocrinology Clinical Practice Guideline for the Diagnosis and Management of Nonalcoholic Fatty Liver Disease in Primary Care and Endocrino...
Biopsy-Controlled Liver Fibrosis Staging Using the Enhanced Liver Fibrosis (ELF) Score Compared to Transient Elastography. K,Rosenberg W,Vaske B, et al.Biopsy-Controlled Liver Fibrosis Staging Using the Enhanced Liver Fibrosis (ELF) Score Compared to Transient Elastography. Pl... Wahl,Kristin,...
The biological stability of direct serum markers (HA, PIIINP and TIMP-1) using HCV-infected samples cryopreserved for 20 years is good. Therefore, the diagnostic accuracy of the ELFscore to identify significant fibrosis and clinical events during follow-up is very high. 展开 ...
FIB-4 Index Panel with Reflex to Enhanced Liver Fibrosis (ELF) Score - This reflex provides a cost-effective, medically justified, and guideline supported approach to evaluating a patient at risk of NAFLD with liver fibrosis. If the FIB-4 index is ...
Besides adipose tissue and liver, skeletal muscle is another main target of SFN. The insulin resistance of skeletal muscle was relieved by SFN administration with company of activated AMPK and NRF2 signaling pathway [33]. SFN could inhibit TGFβ activity to attenuate muscle fibrosis [34]. Our wo...
The macrophage activation marker sCD163 combined with markers of the Enhanced Liver Fibrosis (ELF) score predicts clinically significant portal hypertensio... The macrophage activation marker sCD163 combined with markers of the Enhanced Liver Fibrosis (ELF) score predicts clinically significant portal ...
Previous studies have established high diagnostic accuracy of the ELF score to assess hepatic fibrosis in chronic viral hepatitis and fatty liver disease.ObjectivesThe aim of the research was the evaluation of the usefulness of ELF markings, by patients treated with MTX, as an indicator which shows...
The diagnostic accuracy of the ELF score for liver fibrosis and the effect of age on the ELF score were investigated. Results: The median (interquartile) ELF scores in F0, F1, F2, F3, and F4 are 8.7 (8.2–9.2), 9.3 (8.8–10.0), 10.1 (9.4–10.7), 10.7 (9...
A Cox proportional hazards model showed fully adjusted HRs of 75 (ELF score 12.52-16.67), 20 (10.426-12.51) and 5 (8.34-10.425) compared with patients with ELF <8.34. A unit change in ELF is associated with a doubling of risk of liver-related outcome. An ELF test can predict clinical ...