Biomaterials have evolved from inert materials that lack interaction with the body to biologically active, instructive materials that host and provide signals to surrounding cells and tissues. Engineered living materials contain living cells (responsive
Engineered living biomaterials. Nat. Rev. Mater. 6, 1175–1190 (2021). Article ADS Google Scholar Gilbert, C. et al. Living materials with programmable functionalities grown from engineered microbial co-cultures. Nat. Mater. 20, 691–700 (2021). Article ADS CAS PubMed Google Scholar McBee...
biomaterialsengineered living materialsself‐healingsmart materialssynthetic biologyThe world in a biofilm: in article number 1704847, Neel S. Joshi and co﹚orkers present a detailed review of the rapidly emerging field of engineered living materials (ELMs), in which living cells assimilate resources ...
Engineered living biomaterials Article 31 August 2021 Scaffold-free cell-based tissue engineering therapies: advances, shortfalls and forecast Article Open access 29 March 2021 Ultrasound-assisted tissue engineering Article 02 April 2024 References Langer, R. & Vacanti, J. Tissue engineering. Science...
Leveraging human cells as materials precursors is a promising approach for fabricating living materials with tissue-like functionalities and cellular programmability. Here we describe a set of cellular units with metabolically engineered glycoproteins that allow cells to tether together to function as macro...
living therapeutics synthetic biology biomaterials drug delivery hydrogels Engineered bacterial therapeutics in clinical trials The feasibility of using live engineered bacteria to treat diseases has been explored for nearly three decades [1., 2., 3., 4.]. Several promising candidates have been tested ...
Recent scientific developments in biomaterials and cell biology have led to important milestones in biofabrication [12], most notably in the field of tissue engineering and organ-on-chip (OoC) devices. Regarding OoC systems, these have been adapted to reproduce micro-fluidic and macro-fluidic microp...
Biomaterials , 2021 , 269: 120467 CrossRef Google Scholar [43] Wang M, Altinoglu S, Takeda Y S, et al. Integrating protein engineering and bioorthogonal click conjugation for extracellular vesicle modulation and intracellular delivery. PLoS ONE , 2015 , 10: e0141860 CrossRef ADS Google...
Abstract. Extracellular vesicles (EVs) are heterogeneous membrane-like vesicles secreted by living cells that are involved in many physiological and pathol
Microfluidic-engineered hydrogel microspheres have emerged as a promising avenue for advancements in tissue engineering and regenerative medicine, particularly through the precise manipulation of fluids to achieve personalized composite biomaterials. In this study, we employed microfluidic technology to fabricate...