Microinflammation and endothelial damage in hemodialysis. Contrib Nephrol 2008; 161: 83-88.Merino A,Nogueras S,Buendia P,et al.Microinflammation andendothelial damage in hemodialysis. Contributions to Nephrology . 2008Merino A;Nogueras S;Buendia P;.Microinflammation and endothelial damage in ...
ROS treatment is related to the pathophysiology of endothelial damage and inflammation, so we modeled the leakage of the endothelial barrier of the HUVECs cultured on Col-ANM by treating ROS. On day 5, when the integrity of tight junctions and adherens junctions was maximized, we induced ...
Neutrophils Neutrophils (PMNs) are an integral part of the innate immunity arsenal that protects against invading pathogens such as bacteria but also in "sterile inflammation" (in the absence of pathogens) that occurs as a consequence of hypoxia/reperfusion injury, wound repair, and crystal-induced...
Thede novoactivation of autoreactive T cells by self-antigens that have been released after T- or B-cell-mediated bystander damage. About this article Cite this article Pober, J., Sessa, W. Evolving functions of endothelial cells in inflammation.Nat Rev Immunol7, 803–815 (2007). https:/...
However, under these conditions very little tissue factor is exposed to the blood; instead it is sequestered under the endothelium and presumably becomes exposed only when significant vascular damage is present. Inhibition of intravascular coagulation by factor IXai without impairment of extravascular ...
Upon acute inflammation, neutrophils are the first cells to be recruited into the lungs (Grommes and Soehnlein2011). In contrast to other vascular beds, in the lungs neutrophils transmigrate across the capillary endothelium. Stimulation of neutrophils with various inflammatory agents causes cytoskeletal ...
the mechanisms that disrupt the delicate balance between endothelial damage and repair will be given. Finally, the effects of lifestyle interventions and pharmacotherapy on endothelial dysfunction will be reviewed. 1. Introduction Society is faced with a new pandemic. Obesity and its associated non-...
The testing and monitoring of include tests of endothelium-dependent vasomotion, as well as circulating markers of endothelial damage. Further methods are needed to build up a panel of tests which measure the extent of (= subclinical ), predict the subsequent risk and response to therapy. 展开 ...
et al. Ionizing radiation promotes the acquisition of a senescence-associated secretory phenotype and impairs angiogenic capacity in cerebromicrovascular endothelial cells: role of increased DNA damage and decreased DNA repair capacity in microvascular radiosensitivity. J. Gerontol. A Biol. Sci. Med. Sci...
nonimmune cells, such as endothelial cells (ECs), is also a force to be reckoned with3. The transcriptional upregulation of pro-inflammatory genes by PRRs triggers a cascade of inflammatory responses. Although inflammation has the beneficial effect of limiting cellular and organ damage, disruption...