Endoplasmic Reticulum is a network of membranous tubules present within the cytoplasm of a eukaryotic cell. There are two regions and they differ in both structure and its function.
Tepikin. Endoplasmic reticulum-plasma membrane junctions: structure, function and dynamics. J Phys- iol, 594(11):2837-2847, Jun 2016.Okeke E, Dingsdale H, Parker T, Voronina S, Tepikin AV. Endoplasmic reticulum- plasma membrane junctions: structure, function and dynamics. J Physiol. 2016; ...
Learn about the endoplasmic reticulum (ER), one of the organelles found in the cytoplasm of a cell. Discover the two types of endoplasmic...
ER-PM junctions: Structure, function and dynamics Endoplasmic reticulum (ER)-plasma membrane (PM) junctions are contact sites between the ER and the PM; the distance between the two organelles in the junctions is below 40nm and the membranes are connected by protein tethers. A number of... ...
Interaction with Newly Synthesized and Retained Proteins in the Endoplasmic Reticulum Suggests a Chaperone Function for Human Integral Membrane Protein IP90 (Calnexin) J Biol Chem, 268 (1993), pp. 9585-9592 View PDFView articleView in ScopusGoogle Scholar Human calnexin has the carboxy-terminal seque...
The endoplasmic reticulum (ER) structure is composed from the outer nuclear envelope, and consists of sheets and tubules. Here we describe a variety of labels available to distinguish morphology in both live and fixed cells. These ER labels are highly selective, allowing researchers...
The disruption of the energy or nutrient balance is the fundamental cause of endoplasmic reticulum (ER) stress, a process that mobilizes corrective strategies to reestablish ER and cellular homeostasis known as the unfolded protein response (UPR). In cardiac tissue, numerous conditions can disrupt th...
Calnexin (Cnx) and calreticulin (Crt), which are important chaperones in the endoplasmic reticulum (ER), participate in the folding and quality control of client proteins. Cnx and Crt identified from Chinese mitten crab (Eriocheir sinensis) are designated as EsCnx and EsCrt, respectively. EsCnx ...
2Endoplasmic reticulum: structure and function TheERis a major endomembrane compartment consisting of an extensively folded tubulovesicular membrane network supported by the gel-like cytoplasmic matrix (reviewed inEnglish and Voeltz, 2013). There are two types of ER in a cell: the smooth ER and th...
In our study, Cd is believed to induce mitochondrial dysfunction and endoplasmic reticulum stress (ERS) in a dose-dependent manner, thereby leading to apoptosis, as evident by elevated Drp1, Fis1, GRP78, CHOP, ATF4, P-EIF2α, P-PERK, BAX, cleaved caspase 3 proteins expression and ROS ...