endoplasmic reticulum蛋白质29(ERP.29):一个新兴作用在癌症 翻译结果5复制译文编辑译文朗读译文返回顶部 内质蜂巢胃蛋白质29 (ERp29) : 在癌症的一个涌现的角色 相关内容 awho never betray and abandon is best friend. 谁从未背叛,并且摒弃是最好的朋友。[translate] ...
) of them localize at the rough endoplasmic reticulum's surface because they are vital for its job, which is protein synthesis. The RER exists as stacked sheets that twist together, with helix-shaped edges.
—what the endoplasmic reticulum does is to think of it like a factory. In a manufacturing plant, people take raw materials and make it into something new and usable, which they then ship to other stores, manufacturers, and suppliers around the world.Just like a real-world factory, the end...
Persistent endoplasmic reticulum (ER) stress is thought to drive the pathology of many chronic disorders due to its potential to elicit aberrant inflammatory signaling and facilitate cell death. In neurodegenerative diseases, the accumulation of misfolded proteins and concomitant induction of ER stress in...
Endoplasmic reticulum stress: cell life and death decisions. J Clin Invest. 2005;115(10):2656–64. Article CAS PubMed PubMed Central Google Scholar Kim I, Xu W, Reed JC. Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities. Nat Rev Drug Discov. 2008;...
ER, endoplasmic reticulum–retained podocin mutants; V, vesicular podocin mutants; PM, plasma membrane localized podocin mutants. Interestingly, we observed three specific bands for both Podwt and PodR138Q on podocin immunoblots. The fastest migrating band (lower band) was predominantly observed in ...
. This mechanism provides real-time surveillance for proteins during the entire journey form ribosomes to their final destination. This notion is supported by the ubiquitination of PHOSPHATE TRANSPORTER1, which was regulated by ubiquitin-conjugating enzyme PHO2/UBC24 in post-endoplasmic reticulum [80]...
The endoplasmic reticulum (ER)2 is an important organelle functioning in protein folding, transport, processing, and storage of calcium ion. Homeostasis of ER is crucial for cellular activity and survival (1., 2., 3.). Intracellular and extracellular conditions that interfere with ER function lead...
Herein, we aimed at investigating whether circ_002117 mediates gastric cancer progression through endoplasmic reticulum (ER) stress. Methods Bioinformatics analysis detected differentially expressed circRNAs and their target miRNA candidates, and RT-qPCR was performed to detect expression of circ_002117, ...
The endoplasmic reticulum (ER) is a membranous organelle that maintains proteostasis and cellular homeostasis, controlling the fine balance between health and disease. Dysregulation of the ER stress response has been implicated in intestinal inflammation associated with inflammatory bowel disease (IBD), a...