BACKGROUND Atypical endometrial hyperplasia(AEH)is a common precancerous lesion of endometrial carcinoma(EC).The risk factors for AEH and EC directly or indirectly related to estrogen exposure include early menarche,nulliparity,polycystic ovarian syndrome,diabetes,and obesity.Both AEH and EC rarely occu...
Fig. 8.Cancer outcomes of EIN. A total of 674 patients with various forms of endometrial hyperplasia were reclassified as EIN (red) or benign endometrial hyperplasia (blue) and followed for a median of over 5 years. The curve shows the proportion of each group...
Endometrial hyperplasia, if left untreated or poorly managed, can lead to various complications, the most significant being the development of endometrial cancer. The abnormal proliferation of endometrial cells increases the risk of malignant transformation, particularly in cases of complex or atypical endo...
SUMMARY ANSWER Relapse of complex endometrial hyperplasia after initial regression occurs often and it occurs less often in women treated with LNG-IUS than with oral progestogens. WHAT IS KNOWN ALREADY The LNG-IUS and oral progestogens are used to treat women with endometrial hyperplasia and ...
Ørbo A, Arnes M, Lyså LM et al (2015) Expression of PAX2 and PTEN correlates to therapy response in endometrial hyperplasia. Anticancer Res 35(12):6401–6409 PubMedGoogle Scholar Orr C, Wang C, Firat C et al (2022) Primary clonal loss of mismatch repair protein on immunohistochemistr...
Campbell PE, Barter RA (1961) The significance of atypical endometrial hyperplasia. J Obstet Gynaecol Br Commonw 68: 668 ArticleCASPubMedGoogle Scholar Cavazos F, Lucas FV (1973) Ultrastructure of the endometrium. In: Norris HT, Hertig AT, Abel MR (eds). The uterus. Baltimore, Williams &...
Benign endometrial hyperplasia: diffuse topography caused by prolonged estrogen effect. Treatment: hormonal therapy for symptomatic relief. • Endometrial intraepithelial neoplasia: focal progressing to diffuse topography, which is considered precancerous. Treatment: hormonal therapy or surgery. • Endometria...
(BMI) less than 28; 4) no hormone therapy at least 2 months before surgery; 5) no known gynecological diseases, such as pelvic inflammatory disease (PID), cancers, endometrial hyperplasia, or endometrial polyp; 6) no sexually transmitted diseases (STD), such as HIV, hepatitis B and C, ...
This cohort study evaluates the risk of endometrial polyps, hyperplasia, carcinoma, and uterine cancer after tamoxifen treatment among premenopausal
The role of transvaginal sonography (TVS) in screening endometrial cancer and hyperplasia is significant in postmenopausal women. The objective of this study is to determine the endometrium thickness (ET) cut-off to distinguish premalignancy and malignancy in asymptomatic postmenopausal women. Methods ...