Using a surgically induced menopause mouse model, we assessed the impact of exogenous estrogen and/or PBDEs on mammary glands. At 9 weeks old, female BALB/cj mice underwent ovariectomy (OVX, Fig.1a). The surgery produced expected changes to mammary gland structures, since this model was previo...
Venn diagram depicting the number of different and common miRNAs identified as downregulated after transient HNRNPA2B1 overexpression in MCF-7 cells after 48 or 72 h. MetaCore Enrichment by Pathway Maps analysis of DE downregulated miRNAs after 48 h and 72 h (both versus control) identified...
The oocyte is the starting point for a new generation. Most of the machinery for DNA and protein synthesis needed for the developing embryo is made autonomously by the fertilized oocyte. However, in fish and in many other oviparous vertebrates, the major
environmental hormones, xenoestrogens, hormone-related toxicants, and phytoestrogens all have one thing in common, namely, they describe synthetic chemicals and natural plant or animal compounds that may affect the endocrine system (the biochemical messengers or communication systems of glands, hormones ...