Kodampur M, Kopeika J, Mehra G, Pepera T, Menon P. Endocervical crypt involvement by high-grade cervical intraepithelial neoplasia after large loop excision of transformation zone: do we need a different follow-up strategy? J Obstet Gynaecol Res 2013;39(01): 280-286...
Given the extent of the lesion and since the colposcopy was inadequate, the patient underwent a type 3 large loop excision of the transformation zone and a curettage of the endocervix under local anesthesia. The pathological diagnosis from cervical biopsy revealed an in situ adenocarcinoma of the ...
Located in the upper part of the endocervical canal (rather than at the transformation zone) and usually confined to the inner half of the cervix (Minerva Chir 1989;44:1107) Pathophysiology LEGH is part of the spectrum of pyloric gland metaplasia in the uterine cervix (Am J Surg Pathol 200...
Diagnostic challenges in colposcopy arise especially in women aged 50 or older, with postmenopausal status and transformation zone type 3 (TZ3). Endocervical curettage (ECC) is a valuable tool for diagnosing intracervical lesions. The aim of this retrospective analysis was to evaluate the use of ...
All adenocarcinomas were located proximally on the cervix, and did not involve the transformation zone. Adjacent to carcinoma tissues in the cervix, lobular endocervical glandular hyperplasia was detected. The cells of lobular endocervical glandular hyperplasia were dominantly positive with neutral mucin,...
We used the fixed effects model for meta-analysis.Main results There were 4 eligible studies included in the present systematic review that evaluated 1088 women treated with either large loop excision of the transformation zone (LLETZ) or with cold knife conization (CKC). We found no significant...
No significant lesion was present on follow-up of these cases. For clinicians using our laboratory, large loop excision of the transformation zone (LLETZ) or cone biopsy should follow a 'definite' cytological diagnosis of a high-grade endocervical glandular lesion. However, cone biopsy may not ...
In approximately 25% of uterine cervices there are bundles of smooth muscle in the immediate submucosa of the endocervix usually in the region of the transformation zone. They are morphologically and immunohistochemically different from the inherent muscle deeper in the cervix in that they have more...